Ruthenacyclic carbamoyl mimics of the [Fe]-hydrogenase active site: Derivatisation at the 4-position of the pyridinyl ring

The ruthenacyclic carbamoyl complexes [RuBr(2-NHC(O)C5H3N-4-R)(CO)(2)(MeCN)] in which the 4-position of the pyridinyl ring is derivatized, have been synthesized. These are ruthenium-based structural mimics of the natural [Fe]-hydrogenase metal cofactor. The derivative with R = H reacts with phosphine to form a disubstituted product [RuBr(2-NHC(O)C5H4N)(CO)(PPh2SPh)(2)]. (C) 2020 Elsevier Ltd. All rights reserved.

Automated summary

The ruthenacyclic carbamoyl complexes with derivatized 4-position of the pyridinyl ring have been synthesized, serving as structural mimics of the metal cofactor of [Fe]-hydrogenase. The derivative with R = H reacts with phosphine to form a disubstituted product.