4.6 Article

Activation of TRPV4 by mechanical, osmotic or pharmaceutical stimulation is anti-inflammatory blocking IL-1 beta mediated articular cartilage matrix destruction

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Medicine, Research & Experimental

TRPV4 channel opening mediates pressure-induced pancreatitis initiated by Piezo1 activation

Sandip M. Swain et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Multidisciplinary Sciences

TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension

Christopher L. Gilchrist et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Pharmacology & Pharmacy

Modulation of the TRPV4 ion channel as a therapeutic target for disease

Megan S. Grace et al.

PHARMACOLOGY & THERAPEUTICS (2017)

Article Physiology

In vitro and in vivo evidence for an inflammatory role of the calcium channel TRPV4 in lung epithelium: Potential involvement in cystic fibrosis

Clemence O. Henry et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2016)

Article Biochemistry & Molecular Biology

Endothelial primary cilia inhibit atherosclerosis

Colin Dinsmore et al.

EMBO REPORTS (2016)

Article Multidisciplinary Sciences

Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain

Patrick Kanju et al.

SCIENTIFIC REPORTS (2016)

Article Cell & Tissue Engineering

REDUCED TISSUE OSMOLARITY INCREASES TRPV4 EXPRESSION AND PRO-INFLAMMATORY CYTOKINES IN INTERVERTEBRAL DISC CELLS

B. A. Walter et al.

EUROPEAN CELLS & MATERIALS (2016)

Article Genetics & Heredity

A mutation in TRPV4 results in altered chondrocyte calcium signaling in severe metatropic dysplasia

Lauren Hurd et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2015)

Article Orthopedics

Lithium chloride prevents interleukin-1 induced cartilage degradation and loss of mechanical properties

Clare L. Thompson et al.

JOURNAL OF ORTHOPAEDIC RESEARCH (2015)

Article Multidisciplinary Sciences

Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly

Jie Ran et al.

SCIENTIFIC REPORTS (2015)

Article Multidisciplinary Sciences

aPKC Phosphorylation of HDAC6 Results in Increased Deacetylation Activity

Yifeng Du et al.

PLOS ONE (2015)

Article Physiology

TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury

Shrilatha Balakrishna et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)

Article Multidisciplinary Sciences

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

Whasil Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading

Christopher J. O'Conor et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Rheumatology

Increased susceptibility of Trpv4-deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet

Christopher J. O'Conor et al.

ANNALS OF THE RHEUMATIC DISEASES (2013)

Article Dentistry, Oral Surgery & Medicine

MicroRNA-203 up-regulates nitric oxide expression in temporomandibular joint chondrocytes via targeting TRPV4

Fang Hu et al.

ARCHIVES OF ORAL BIOLOGY (2013)

Review Biochemistry & Molecular Biology

The puzzle of TRPV4 channelopathies

Bernd Nilius et al.

EMBO REPORTS (2013)

Article Biochemistry & Molecular Biology

Extracellular Signal-regulated Kinase (ERK) Phosphorylates Histone Deacetylase 6 (HDAC6) at Serine 1035 to Stimulate Cell Migration

Kendra A. Williams et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

Primary cilia elongation in response to interleukin-1 mediates the inflammatory response

A. K. T. Wann et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2012)

Article Biochemistry & Molecular Biology

2-Deoxy-D-glucose regulates dedifferentiation through β-catenin pathway in rabbit articular chondrocytes

Sean-Mi Yu et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2010)

Article Pharmacology & Pharmacy

TRPV4-Like Non-selective Cation Currents in Cultured Aortic Myocytes

Ryoichi Tanaka et al.

JOURNAL OF PHARMACOLOGICAL SCIENCES (2008)

Article Cell Biology

Intracellular trafficking of TRP channels

Sylvie Cayouette et al.

CELL CALCIUM (2007)

Article Biochemistry & Molecular Biology

HEF1-Dependent aurora a activation induces disassembly of the primary cilium

Elena N. Pugacheva et al.

Article Biochemistry & Molecular Biology

Microtubule acetylation promotes kinesin-1 binding and transport

Nathan A. Reed et al.

CURRENT BIOLOGY (2006)

Article Cell Biology

TRPV4 exhibits a functional role in cell-volume regulation

D Becker et al.

JOURNAL OF CELL SCIENCE (2005)

Article Multidisciplinary Sciences

Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4

J Vriens et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Osmotic stress, a proinflammatory signal in Caco-2 cells

A Hubert et al.

BIOCHIMIE (2004)

Article Biochemistry & Molecular Biology

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

A Matsuyama et al.

EMBO JOURNAL (2002)

Article Biochemistry & Molecular Biology

Dynamic compression inhibits the synthesis of nitric oxide and PGE2 by IL-1β-stimulated chondrocytes cultured in agarose constructs

TT Chowdhury et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)

Article Multidisciplinary Sciences

Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5

TA McKinsey et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Biochemistry & Molecular Biology

Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4

HD Youn et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)