Organocatalytic Kinetic Resolution of N-Boc-Isoxazolidine-5-ones

Easily accessible racemic N-Boc-isoxazolidine-5-ones undergo enantioselective alcoholysis promoted by double hydrogen bond donor amine organocatalysts, resulting in their effective kinetic resolution.

Automated summary

In summary, easily accessible racemic N-Boc-isoxazolidine-5-ones can undergo enantioselective alcoholysis promoted by double hydrogen bond donor amine organocatalysts, leading to their effective kinetic resolution.