期刊
ONCOLOGY RESEARCH
卷 28, 期 5, 页码 533-540出版社
TECH SCIENCE PRESS
DOI: 10.3727/096504020X15919605976853
关键词
CD13; Multidrug resistance (MDR); Drug efflux; Chemotherapy; Reactive oxygen species; Immune suppression
类别
Cancer is one of the most serious diseases that are harmful to human health. Systemic chemotherapy is an optimal therapeutic strategy for the treatment of cancer, but great difficulty has been encountered in its administration in the form of multidrug resistance (MDR). As an enzyme on the outer cell surface, CD13 is documented to be involved in the MDR development of tumor cells. In this review, we will focus on the role of CD13 in MDR generation based on the current evidence.
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