期刊
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
卷 31, 期 4, 页码 1121-1128出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.numecd.2020.12.028
关键词
Nutritional Risk Screening 2002; Acute kidney injury; Acute coronary syndrome; Mortality; Prognosis
资金
- Sichuan Science and Technology Program [2020YFS0154, 2020YFSY0014, 2019JDRC0105]
- Sichuan University West China Hospital [2018HXFH001, 2018HXFH027, 20HXFH050]
- West China School of Nursing, Sichuan University [HXHL19023, HXHL20046]
- National Key R&D Program of China [2017YFC0908702]
- Chengdu Science and Technology Bureau [2019-YF05e00322-SN]
This study aimed to evaluate the impact of malnutrition risk assessed using NRS-2002 on AKI and mortality in ACS patients. The results indicated a significant association between malnutrition risk, AKI, and mortality, suggesting further nutritional intervention and AKI prevention for ACS patients.
Background and aims: Acute kidney injury (AKI) is a common complication of acute coronary syndrome (ACS), and is associated with increased risk of morbidity and mortality. We aimed to evaluate the impact of malnutrition risk at admission assessed using Nutritional Risk Screening 2002 (NRS-20 02) on AKI and mortality in patients with ACS. Methods and results: We enrolled 3185 ACS patients from the retrospective multi-centre study. AKI was defined as criteria of the 2012 Kidney Disease Improving Global Outcomes. Risk of malnutrition was defined as NRS-20 02 score 3 vs. 3) for AKI and mortality were 1.643 (95% confidence interval: 1.242-2.172, P < 0.001) and 2.026 (95% confidence interval: 1.491-2.753, P < 0.001), respectively. In structural equation modelling, the indirect effects of NRS-20 02 on mortality via AKI were 54.1% (P < 0.001). Conclusion: The risk of malnutrition assessed using NRS-20 02 was useful in identifying high-risk patients with AKI and mortality, and patients with ACS may benefit from further nutritional intervention and prevention of AKI. Registration number: ChiCTR1900024657. ? 2021 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.
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