Vitamin D is not associated with body composition and metabolic profile among Brazilian children with 25-hydroxyvitamin D > 75 nmol/L: A cross-sectional study

Background and aims: The association of vitamin D with cardiovascular disease risk factors among children remains inconclusive, and there is a lack of studies that evaluate children with optimal serum 25-hydroxyvitamin D [25(OH)D]. Thus, this study aimed to analyze the relationship between serum 25(OH)D and body composition and metabolic profile among Brazilian children with sufficient serum 25(OH)D. Methods and results: A cross-sectional study was conducted with 88 Brazilian children aged 4-11 years. Self-reported race, physical activity, anthropometry (body mass and height), body composition (waist circumference, body fat percentage, fat free mass, triceps and subscapular skinfolds), biochemical profile [lipid fractions, fasting glucose and 25(OH)D] and blood pressure data were collected. No difference was found in sex, self-reported race, physical activity, age, anthropometry, body composition, biochemical parameters and blood pressure between children with 25(OH)D 75-99 and > 100 nmol/L. In addition, there was no association between serum vitamin D and body composition and metabolic profile. Conclusions: Serum 25(OH)D was not associated with body composition and metabolic profile among Brazilian children with sufficient serum 25(OH)D. Further studies among children with serum levels > 75 nmol/L are needed to confirm this finding. @& nbsp;2020 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Automated summary

This study found no association between serum 25(OH)D levels and body composition and metabolic profile among Brazilian children, suggesting that children with sufficient serum 25(OH)D levels may not need to worry about health issues related to body composition and metabolism. Further research is needed to confirm these findings.