期刊
NEW PHYTOLOGIST
卷 229, 期 6, 页码 3453-3466出版社
WILEY
DOI: 10.1111/nph.17122
关键词
Arabidopsis thaliana; fungal elicitor; Fusarium; leucine-rich repeat receptor-like kinase; MDIS1-INTERACTING RECEPTOR LIKE KINASE 2; pattern-recognition receptor; pattern-triggered immunity; plant immunity
资金
- BASF Plant Science Company GmbH (RD cooperation)
- German Research Foundation [HU886/11]
- NWO [865.14.00]
- DFG Emmy Noether program [RA2541/1]
This study investigated the immune response of Arabidopsis thaliana to Fusarium elicitors and identified the crucial role of MIK2 in perceiving fungal elicitors in plants, along with the signaling pathways involved. These findings provide important insights for improving resistance in crops against fungal pathogens.
Fusarium spp. cause severe economic damage in many crops, exemplified by Panama disease of banana or Fusarium head blight of wheat. Plants sense immunogenic patterns (termed elicitors) at the cell surface to initiate pattern-triggered immunity (PTI). Knowledge of fungal elicitors and corresponding plant immune-signaling is incomplete but could yield valuable sources of resistance. We characterized Arabidopsis thaliana PTI responses to a peptide elicitor fraction present in several Fusarium spp. and employed a forward-genetic screen using plants containing a cytosolic calcium reporter to isolate fusarium elicitor reduced elicitation (fere) mutants. We mapped the causal mutation in fere1 to the leucine-rich repeat receptor-like kinase MDIS1-INTERACTING RECEPTOR-LIKE KINASE 2 (MIK2) and confirmed a crucial role of MIK2 in fungal elicitor perception. MIK2-dependent elicitor responses depend on known signaling components and transfer of AtMIK2 is sufficient to confer elicitor sensitivity to Nicotiana benthamiana. Arabidopsis senses Fusarium elicitors by a novel receptor complex at the cell surface that feeds into common PTI pathways. These data increase mechanistic understanding of PTI to Fusarium and place MIK2 at a central position in Arabidopsis elicitor responses.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据