Neurological issues in children with COVID-19

Coronavirus disease 2019 (COVID-19) usually leads to a mild infectious disease course in children, but serious complications may occur in conjunction with both acute infection and associated phenomena such as the multisystem inflammatory syndrome in children (MIS-C). Neurological symptoms, which have been predominantly reported in adults, range from mild headache to seizure, peripheral neuropathy, stroke, demyelinating disorders, and encephalopathy. Similar to respiratory and cardiac manifestations of COVID-19, neurological complications present differently based on age and underlying comorbidities. This review provides a concise overview of the neurological conditions seen in the context of COVID-19, as well as potential mechanisms and long-term implications of COVID-19 in the pediatric population from literature reviews and primary data collected at NewYork-Presbyterian Morgan Stanley Children's Hospital.

Automated summary

COVID-19 typically causes mild infection in children, but serious complications such as neurological symptoms can occur, varying in presentation depending on age and underlying conditions. The review provides an overview of neurological conditions associated with COVID-19 in children and discusses potential mechanisms and long-term implications based on literature reviews and primary data collected at NewYork-Presbyterian Morgan Stanley Children's Hospital.