期刊
DOKLADY BIOCHEMISTRY AND BIOPHYSICS
卷 471, 期 1, 页码 410-412出版社
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1607672916060090
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资金
- Russian Science Foundation [14-15-00245]
- Russian Science Foundation [14-15-00245] Funding Source: Russian Science Foundation
It is shown that endothelial cells from human umbilical vein have a reduced activity and gene expression of the classic antioxidant enzymes (Cu,Zn-superoxide dismutase, catalase, and Se-containing glutathione peroxidase). At the same time, a high expression level of peroxiredoxin genes was identified in the same endothelial cells, which obviously indicates the predominant involvement of these enzymes in protecting the endothelium from the damaging effect of free radical peroxidation.
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