Unravelling the complex genetic regulation of immune cells

Genetic variation contributes to immune cell function. An unprecedented analysis of genetic associations with immune cell traits provides insights into the complex regulation of immune cells, reveals variants that coincidently influence immune traits and autoimmune disease risk, and offers specific therapeutic targets for these diseases.

Automated summary

Genetic variation plays a crucial role in immune cell function. An in-depth analysis of genetic associations with immune cell traits sheds light on the complex regulation of immune cells, identifies variants influencing immune traits and autoimmune disease risk simultaneously, and suggests specific therapeutic targets for these diseases.