Trained immunity, tolerance, priming and differentiation: distinct immunological processes

The similarities and differences between trained immunity and other immune processes are the subject of intense interrogation. Therefore, a consensus on the definition of trained immunity in both in vitro and in vivo settings, as well as in experimental models and human subjects, is necessary for advancing this field of research. Here we aim to establish a common framework that describes the experimental standards for defining trained immunity.

Automated summary

Researchers are working towards establishing a set of experimental standards to reach consensus on defining trained immunity, which will help advance research in this field.