Mitochondria orchestrate T cell fate and function

An investigation of the molecular processes of mitochondrial reprogramming and metabolic stress in antigen-experienced T cells within tumor microenvironments reveals mechanisms responsible for T cell exhaustion and dysfunction and facilitates the development of new strategies for tumor immunotherapy.

Automated summary

Investigation of molecular processes related to mitochondrial reprogramming and metabolic stress in antigen-experienced T cells within tumor microenvironments reveals mechanisms underlying T cell exhaustion and dysfunction, aiding in the development of novel strategies for tumor immunotherapy.