相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。DNA-Encoded Library Screening as Core Platform Technology in Drug Discovery: Its Synthetic Method Development and Applications in DEL Synthesis
Minsoo Song et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Future challenges with DNA-encoded chemical libraries in the drug discovery domain
Guixian Zhao et al.
EXPERT OPINION ON DRUG DISCOVERY (2019)
Encoded Library Technologies as Integrated Lead Finding Platforms for Drug Discovery
Johannes Ottl et al.
MOLECULES (2019)
Next-Generation Glycan Microarray Enabled by DNA-Coded Glycan Library and Next-Generation Sequencing Technology
Maomao Yan et al.
ANALYTICAL CHEMISTRY (2019)
Aptamer-Directed Conjugation of DNA to Therapeutic Antibodies
Mikkel B. Skovsgaard et al.
BIOCONJUGATE CHEMISTRY (2019)
Application of a Substrate-Mediated Selection with c-Src Tyrosine Kinase to a DNA-Encoded Chemical Library
Dongwook Kim et al.
MOLECULES (2019)
Aptamer Displacement Reaction from Live-Cell Surfaces and Its Applications
Long Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
Selection of DNA-Encoded Libraries to Protein Targets within and on Living Cells
Bo Cai et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome
Hans Richter et al.
ACS CHEMICAL BIOLOGY (2019)
Chemistry for Covalent Modification of Endogenous/Native Proteins: From Test Tubes to Complex Biological Systems
Tomonori Tamura et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
DNA Hybridization to Control Cellular Interactions
Ariel L. Furst et al.
TRENDS IN BIOCHEMICAL SCIENCES (2019)
Chemical composition of DNA-encoded libraries, past present and future
Paige Dickson et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2019)
Beyond protein binding: recent advances in screening DNA-encoded libraries
Thomas Kodadek et al.
CHEMICAL COMMUNICATIONS (2019)
An Integrated Approach Based on a DNA Self-Assembly Technique for Characterization of Crosstalk among Combinatorial Histone Modifications
Xue Bai et al.
ANALYTICAL CHEMISTRY (2018)
New Techniques for the Generation and Analysis of Tailored Microbial Systems on Surfaces
Ariel L. Furst et al.
BIOCHEMISTRY (2018)
Lessons learned from the blockade of immune checkpoints in cancer immunotherapy
Xiaolei Li et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
Small-Molecule Positive Allosteric Modulators of the β2-Adrenoceptor Isolated from DNA-Encoded Libraries
Seungkirl Ahn et al.
MOLECULAR PHARMACOLOGY (2018)
Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules
Dmitry L. Usanov et al.
NATURE CHEMISTRY (2018)
Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target
Dean G. Brown et al.
SLAS DISCOVERY (2018)
DNA-Encoded Chemical Libraries: A Selection System Based on Endowing Organic Compounds with Amplifiable Information
Dario Neri et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 87 (2018)
DNA-Encoded Dynamic Chemical Library and Its Applications in Ligand Discovery
Yu Zhou et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)
Direct Electrochemical Bioconjugation on Metal Surfaces
Ariel L. Furst et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)
Trends in GPCR drug discovery: new agents, targets and indications
Alexander S. Hauser et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Allosteric beta-blocker isolated from a DNA-encoded small molecule library
Seungkirl Ahn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Selecting a DNA-Encoded Chemical Library against Non-immobilized Proteins Using a Ligate-Cross-Link-Purify Strategy
Bingbing Shi et al.
BIOCONJUGATE CHEMISTRY (2017)
Recognition-then-Reaction Enables Site-Selective Bioconjugation to Proteins on Live-Cell Surfaces
Cheng Cui et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Target Identification of Kinase Inhibitor Alisertib (MLN8237) by Using DNA-Programmed Affinity Labeling
Dong-Yao Wang et al.
CHEMISTRY-A EUROPEAN JOURNAL (2017)
Predicting Electrophoretic Mobility of Protein-Ligand Complexes for Ligands from DNA-Encoded Libraries of Small Molecules
Jiayin Bao et al.
ANALYTICAL CHEMISTRY (2016)
Development of a DNA-Templated Peptide Probe for Photoaffinity Labeling and Enrichment of the Histone Modification Reader Proteins
Xue Bai et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Drugging Membrane Protein Interactions
Hang Yin et al.
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 18 (2016)
Membrane proteins: always an insoluble problem?
Andrea E. Rawlings
BIOCHEMICAL SOCIETY TRANSACTIONS (2016)
DNA-Templated Introduction of an Aldehyde Handle in Proteins
Anne Louise B. Kodal et al.
CHEMBIOCHEM (2016)
Automated screening for small organic ligands using DNA-encoded chemical libraries
Willy Decurtins et al.
NATURE PROTOCOLS (2016)
Using modified aptamers for site specific protein-aptamer conjugations
Ruowen Wang et al.
CHEMICAL SCIENCE (2016)
From haystack to needle: finding value with DNA encoded library technology at GSK
Christopher C. Arico-Muendel
MEDCHEMCOMM (2016)
Crosslinking of DNA-linked ligands to target proteins for enrichment from DNA-encoded libraries
Kyle E. Denton et al.
MEDCHEMCOMM (2016)
Quantification of Epidermal Growth Factor Receptor Expression Level and Binding Kinetics on Cell Surfaces by Surface Plasmon Resonance Imaging
Fenni Zhang et al.
ANALYTICAL CHEMISTRY (2015)
Mechanisms and Implications of Dual-Acting Methotrexate in Folate-Targeted Nanotherapeutic Delivery
Pamela T. Wong et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory
Zoe Cournia et al.
JOURNAL OF MEMBRANE BIOLOGY (2015)
Live-Cell Labeling of Specific Protein Glycoforms by Proximity-Enhanced Bioorthogonal Ligation
Peter V. Robinson et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation
Moreno Wichert et al.
NATURE CHEMISTRY (2015)
Photoaffinity labeling of transcription factors by DNA-templated crosslinking
Ying Liu et al.
CHEMICAL SCIENCE (2015)
Design, preparation, and selection of DNA-encoded dynamic libraries
Gang Li et al.
CHEMICAL SCIENCE (2015)
Cell-Based Selection Expands the Utility of DNA-Encoded Small-Molecule Library Technology to Cell Surface Drug Targets: Identification of Novel Antagonists of the NK3 Tachykinin Receptor
Zining Wu et al.
ACS COMBINATORIAL SCIENCE (2015)
Optimization method for obtaining nearest-neighbour DNA entropies and enthalpies directly from melting temperatures
Gerald Weber
BIOINFORMATICS (2015)
Selection of DNA-Encoded Small Molecule Libraries Against Unmodified and Non-Immobilized Protein Targets
Peng Zhao et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Application of encoded library technology (ELT) to a protein-protein interaction target: Discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists
Christopher S. Kollmann et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
LDAI-Based Chemical Labeling of Intact Membrane Proteins and Its Pulse-Chase Analysis under Live Cell Conditions
Takayuki Miki et al.
CHEMISTRY & BIOLOGY (2014)
Advances in DNA-directed immobilization
Rebecca Meyer et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2014)
Identification of Ligand-Target Pairs from Combined Libraries of Small Molecules and Unpurified Protein Targets in Cell Lysates
Lynn M. McGregor et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Photoactivated Bioconjugation Between ortho-Azidophenols and Anilines: A Facile Approach to Biomolecular Photopatterning
Kareem M. El Muslemany et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Template-directed covalent conjugation of DNA to native antibodies, transferrin and other metal-binding proteins
Christian B. Rosen et al.
NATURE CHEMISTRY (2014)
Photoaffinity Labeling of Small-Molecule-Binding Proteins by DNA-Templated Chemistry
Gang Li et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
Exploring avidity: understanding the potential gains in functional affinity and target residence time of bivalent and heterobivalent ligands
Georges Vauquelin et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
DNA-Mediated Assembly of Protein Heterodimers on Membrane Surfaces
Michael P. Coyle et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Multistep DNA-Templated Synthesis Using a Universal Template
Yizhou Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
DNA-Modification of Eukaryotic Cells
Katrin Vogel et al.
SMALL (2013)
Aptamer-Based Affinity Labeling of Proteins
Jan L. Vinkenborg et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Discovery of Small-Molecule Interleukin-2 Inhibitors from a DNA-Encoded Chemical Library
Markus Leimbacher et al.
CHEMISTRY-A EUROPEAN JOURNAL (2012)
Specific Cell Surface Protein Imaging by Extended Self-Assembling Fluorescent Turn-on Nanoprobes
Keigo Mizusawa et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Ligand-Directed Acyl Imidazole Chemistry for Labeling of Membrane-Bound Proteins on Live Cells
Sho-hei Fujishima et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Selection of Carbonic Anhydrase IX Inhibitors from One Million DNA-Encoded Compounds
Fabian Buller et al.
ACS CHEMICAL BIOLOGY (2011)
Regulation of Integrin Activation
Chungho Kim et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Encoded peptide libraries and the discovery of new cell binding ligands
Nina Svensen et al.
CHEMICAL COMMUNICATIONS (2011)
Decoding a PNA Encoded Peptide Library by PCR: The Discovery of New Cell Surface Receptor Ligands
Nina Svensen et al.
CHEMISTRY & BIOLOGY (2011)
Mimicking the inflammatory cell adhesion cascade by nucleic acid aptamer programmed cell-cell interactions
Weian Zhao et al.
FASEB JOURNAL (2011)
In Vitro Selection of a DNA-Templated Small-Molecule Library Reveals a Class of Macrocyclic Kinase Inhibitors
Ralph E. Kleiner et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
BioNumbers-the database of key numbers in molecular and cell biology
Ron Milo et al.
NUCLEIC ACIDS RESEARCH (2010)
A Yoctoliter-Scale DNA Reactor for Small-Molecule Evolution
Margit Haahr Hansen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Control of DNA Strand Displacement Kinetics Using Toehold Exchange
David Yu Zhang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Design, synthesis and selection of DNA-encoded small-molecule libraries
Matthew A. Clark et al.
NATURE CHEMICAL BIOLOGY (2009)
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
Zev J. Gartner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries
Luca Mannocci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Synthetic ligands discovered by in vitro selection
S. Jarrett Wrenn et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
OligoCalc: an online oligonucleotide properties calculator
Warren A. Kibbe
NUCLEIC ACIDS RESEARCH (2007)
Programmable cell adhesion encoded by DNA hybridization
RA Chandra et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
DNA-templated organic synthesis and selection of a library of macrocycles
ZJ Gartner et al.
SCIENCE (2004)
分享论文
