4.8 Article

Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

Isotopically Labeled Desthiobiotin Azide (isoDTB) Tags Enable Global Profiling of the Bacterial Cysteinome

Patrick R. A. Zanon et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Biochemistry & Molecular Biology

Global targeting of functional tyrosines using sulfur-triazole exchange chemistry

Heung Sik Hahm et al.

NATURE CHEMICAL BIOLOGY (2020)

Article Biochemical Research Methods

Full-Featured, Real-Time Database Searching Platform Enables Fast and Accurate Multiplexed Quantitative Proteomics

Devin K. Schweppe et al.

JOURNAL OF PROTEOME RESEARCH (2020)

Article Chemistry, Multidisciplinary

Tunable Heteroaromatic Sulfones Enhance in-Cell Cysteine Profiling

Hashim F. Motiwala et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Chemistry, Analytical

Benchmarking the Orbitrap Tribrid Eclipse for Next Generation Multiplexed Proteomics

Qing Yu et al.

ANALYTICAL CHEMISTRY (2020)

Article Biochemistry & Molecular Biology

An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells

Ekaterina V. Vinogradova et al.

Article Biochemistry & Molecular Biology

Structure and Characterization of a Covalent Inhibitor of Src Kinase

Deepak Gurbani et al.

FRONTIERS IN MOLECULAR BIOSCIENCES (2020)

Article Chemistry, Multidisciplinary

Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening

Efrat Resnick et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Chemistry, Multidisciplinary

The Proteome-Wide Potential for Reversible Covalency at Cysteine

Kristine Senkane et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Review Biochemistry & Molecular Biology

Reactive-cysteine profiling for drug discovery

Aaron J. Maurais et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2019)

Review Pharmacology & Pharmacy

Target 2035: probing the human proteome

Adrian J. Carter et al.

DRUG DISCOVERY TODAY (2019)

Article Biochemistry & Molecular Biology

Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

Xiaoyu Zhang et al.

NATURE CHEMICAL BIOLOGY (2019)

Article Biochemistry & Molecular Biology

Evaluation of Chemically-Cleavable Linkers for Quantitative Mapping of Small Molecule-Cysteinome Reactivity

Adam J. Rabalski et al.

ACS CHEMICAL BIOLOGY (2019)

News Item Biotechnology & Applied Microbiology

A probe for every protein

Asher Mullard

NATURE REVIEWS DRUG DISCOVERY (2019)

Article Biochemical Research Methods

Active Instrument Engagement Combined with a Real-Time Database Search for Improved Performance of Sample Multiplexing Workflows

Brian K. Erickson et al.

JOURNAL OF PROTEOME RESEARCH (2019)

Article Chemistry, Multidisciplinary

A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification

Christopher M. Browne et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Biochemistry & Molecular Biology

Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome

Suman Rao et al.

CELL CHEMICAL BIOLOGY (2019)

Article Biochemistry & Molecular Biology

Fragment-Based Drug Discovery: Advancing Fragments in the Absence of Crystal Structures

Daniel A. Erlanson et al.

CELL CHEMICAL BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Recent Advances in Selective and Irreversible Covalent Ligand Development and Validation

Tinghu Zhang et al.

CELL CHEMICAL BIOLOGY (2019)

Article Biochemistry & Molecular Biology

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

Matthew R. Janes et al.

Article Biochemical Research Methods

Proteome-Wide Evaluation of Two Common Protein Quantification Methods

Jeremy D. O’Connell et al.

JOURNAL OF PROTEOME RESEARCH (2018)

Article Chemistry, Multidisciplinary

Chemoproteomic profiling and discovery of protein electrophiles in human cells

Megan L. Matthews et al.

NATURE CHEMISTRY (2017)

Article Chemistry, Multidisciplinary

Global profiling of lysine reactivity and ligandability in the human proteome

Stephan M. Hacker et al.

NATURE CHEMISTRY (2017)

Article Multidisciplinary Sciences

A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action

Elena Campaner et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer

Liron Bar-Peled et al.

Article Biochemistry & Molecular Biology

Privileged Electrophile Sensors: A Resource for Covalent Drug Development

Marcus John Curtis Long et al.

CELL CHEMICAL BIOLOGY (2017)

Review Biochemical Research Methods

Activity-based protein profiling for mapping and pharmacologically interrogating proteome-wide ligandable hotspots

Allison M. Roberts et al.

CURRENT OPINION IN BIOTECHNOLOGY (2017)

Article Multidisciplinary Sciences

Proteome-wide covalent ligand discovery in native biological systems

Keriann M. Backus et al.

NATURE (2016)

Article Biochemical Research Methods

An in vivo multiplexed small-molecule screening platform

Barbara M. Gruner et al.

NATURE METHODS (2016)

Article Multidisciplinary Sciences

Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism

Piro Lito et al.

SCIENCE (2016)

Article Biochemical Research Methods

A Deeper Look into Comet-Implementation and Features

Jimmy K. Eng et al.

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2015)

Review Biochemical Research Methods

Isobaric Labeling-Based Relative Quantification in Shotgun Proteomics

Navin Rauniyar et al.

JOURNAL OF PROTEOME RESEARCH (2014)

Review Biochemistry & Molecular Biology

Applications of Copper-Catalyzed Click Chemistry in Activity-Based Protein Profiling

Julianne Martell et al.

MOLECULES (2014)

Article Multidisciplinary Sciences

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

Nicholas Kwiatkowski et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors

Bryan R. Lannine et al.

NATURE CHEMICAL BIOLOGY (2014)

Review Biochemistry & Molecular Biology

Diverse Functional Roles of Reactive Cysteines

Nicholas J. Pace et al.

ACS CHEMICAL BIOLOGY (2013)

Article Biochemistry & Molecular Biology

An Isotopically Tagged Azobenzene-Based Cleavable Linker for Quantitative Proteomics

Yu Qian et al.

CHEMBIOCHEM (2013)

Article Biochemical Research Methods

A Simple and Effective Cleavable Linker for Chemical Proteomics Applications

Yinliang Yang et al.

MOLECULAR & CELLULAR PROTEOMICS (2013)

Article Biochemical Research Methods

Comet: An open-source MS/MS sequence database search tool

Jimmy K. Eng et al.

PROTEOMICS (2013)

Article Chemistry, Analytical

Increasing the Multiplexing Capacity of TMTs Using Reporter Ion Isotopologues with Isobaric Masses

Graeme C. McAlister et al.

ANALYTICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

Edward L. Huttlin et al.

Article Multidisciplinary Sciences

Quantitative reactivity profiling predicts functional cysteines in proteomes

Eranthie Weerapana et al.

NATURE (2010)

Article Biochemical Research Methods

Selective Enrichment of Azide-Containing Peptides from Complex Mixtures

Merel A. Nessen et al.

JOURNAL OF PROTEOME RESEARCH (2009)

Article Chemistry, Multidisciplinary

The rise of fragment-based drug discovery

Christopher W. Murray et al.

NATURE CHEMISTRY (2009)

Review Biochemistry & Molecular Biology

Activity-based protein profiling: From enzyme chemistry

Benjamin F. Cravatt et al.

ANNUAL REVIEW OF BIOCHEMISTRY (2008)

Review Biochemistry & Molecular Biology

Expanding the functional diversity of proteins through cysteine oxidation

Khalilah G. Reddie et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Disparate proteome reactivity profiles of carbon electrophiles

Eranthie Weerapana et al.

NATURE CHEMICAL BIOLOGY (2008)

Article Biotechnology & Applied Microbiology

A probability-based approach for high-throughput protein phosphorylation analysis and site localization

Sean A. Beausoleil et al.

NATURE BIOTECHNOLOGY (2006)

Article Biochemistry & Molecular Biology

Multiple roles of cysteine in biocatalysis

NM Giles et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)