期刊
NATURAL PRODUCT RESEARCH
卷 36, 期 5, 页码 1332-1336出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2020.1864369
关键词
Salvia; phenolic compounds; antioxidant activity; antimicrobial activity
资金
- Bu Ali Sina University
This study explores the biological and pharmacological effects of nineteen Salvia multicaulis populations grown in Iran, revealing high antimicrobial and antioxidant activities in some populations, which could be potentially exploited for commercial purposes.
The genus Salvia L. belongs to the Lamiaceae family including several known species rich in natural compounds that are extensively used in pharmaceutical, food, and cosmetic industries. Salvia multicaulis populations contain a broad diversity of flavonoids and phenolic acids. The present study aimed to explore biological and pharmacological effects including antimicrobial and antioxidant activities of nineteen S. multicaulis populations (SMPs) grown in Iran for the first time. High content of rosmarinic acid (RA) in SMP12 (Gazan) (5.65 +/- 0.33 mg/g DW) caused high antimicrobial activity against two bacteria (Staphylococcus aureus, Escherichia coli) and the fungus Candida albicans, while methanolic extract of SMP1 (Taleghan) showed high antioxidant activity due to high content of salvianolic acid A (SAA) and quercetin (0.53 +/- 0.04 and 0.49 +/- 0.12 mg/g DW, respectively). Altogether these results can be considered for further commercial exploitations to meet the demands of the food and pharmaceutical industries.
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