期刊
NATURAL PRODUCT RESEARCH
卷 36, 期 13, 页码 3255-3261出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2020.1851226
关键词
Aspergillus sp; phenolic; glucoside
资金
- Program for Changjiang Scholars of the Ministry of Education of the People's Republic of China [T2016088]
- [National Natural Science Foundation for Distinguished Young Scholars] [81725021]
- Gannan Medical University [QD201832]
- Health and family planning committee of Jiangxi province [2015B031]
- Jiangxi Education Hall Science and Technology Foundation [GJJ190829]
This article reports the isolation and structural elucidation of two new compounds from a marine-derived fungus, as well as the evaluation of their biological activity.
Two new phenolic glucosides, including a new O-glycoside (1) and a new C-glycoside (2), were isolated from a marine-derived fungus Aspergillus sp. The structures of new compounds were elucidated through interpretations of spectroscopic evidence and high-resolution electrospray ionization mass spectrometry. The hexose unit of 1 was identified as beta-D-glucose by comparison with an authentic sample via HPLC after acid hydrolysis and derivatization. All compounds were evaluated for their ability to inhibit LPS-induced NO production in RAW264.7 macrophages, but none of them displayed significant activity.
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