期刊
MOLECULES
卷 26, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/molecules26010229
关键词
resveratrol; absorption and metabolism; anti-inflammation; antioxidant; mechanism
资金
- National Natural Science Foundation of China [31972600, 31872991]
- Natural Science Foundation of Hunan Province-China [2020JJ4364]
- Double first class Construction Project of Hunan Agricultural University [kxk201801004]
- Project of science and Technology Department of Hunan Province [2020NK4247]
Resveratrol, a natural phytoalexin polyphenol, demonstrates antioxidant, anti-inflammatory, and anti-carcinogenic properties, with the ability to modulate inflammatory responses and exhibit immunomodulatory function both in vivo and in vitro.
Resveratrol (3,4 ',5-trihy- droxystilbene), a natural phytoalexin polyphenol, exhibits anti-oxidant, anti-inflammatory, and anti-carcinogenic properties. This phytoalexin is well-absorbed and rapidly and extensively metabolized in the body. Inflammation is an adaptive response, which could be triggered by various danger signals, such as invasion by microorganisms or tissue injury. In this review, the anti-inflammatory activity and the mechanism of resveratrol modulates the inflammatory response are examined. Multiple experimental studies that illustrate regulatory mechanisms and the immunomodulatory function of resveratrol both in vivo and in vitro. The data acquired from those studies are discussed.
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