期刊
MOLECULES
卷 26, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/molecules26030523
关键词
nanoparticles; veterinary medicine; one health; antibiotics; hormones; vaccines
资金
- European Social Found, Human Capital operational Programme 2014-2020 [POCU/380/6/13/125171]
- CNCS-UEFISCDI Romania [PN-III-P1-1.1-MC-2019-0138]
- USDA National Institute of Food and Agriculture AFRI project [2018-07406]
- USDA-NIFA Hatch Project [1008750]
Engineered nanoparticles (ENPs), including polymeric, biodegradable ENPs (pbENPs), have been developed for veterinary applications, but the fate of these ENPs is poorly understood, as their biotransformation greatly affects their impact on health and the environment.
The field of veterinary medicine needs new solutions to address the current challenges of antibiotic resistance and the need for increased animal production. In response, a multitude of delivery systems have been developed in the last 20 years in the form of engineered nanoparticles (ENPs), a subclass of which are polymeric, biodegradable ENPs, that are biocompatible and biodegradable (pbENPs). These platforms have been developed to deliver cargo, such as antibiotics, vaccines, and hormones, and in general, have been shown to be beneficial in many regards, particularly when comparing the efficacy of the delivered drugs to that of the conventional drug applications. However, the fate of pbENPs developed for veterinary applications is poorly understood. pbENPs undergo biotransformation as they are transferred from one ecosystem to another, and these transformations greatly affect their impact on health and the environment. This review addresses nanoparticle fate and impact on animals, the environment, and humans from a One Health perspective.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据