A Review: Halogenated Compounds from Marine Fungi

Marine fungi produce many halogenated metabolites with a variety of structures, from acyclic entities with a simple linear chain to multifaceted polycyclic molecules. Over the past few decades, their pharmaceutical and medical application have been explored and still the door is kept open due to the need of new drugs from relatively underexplored sources. Biological properties of halogenated compounds such as anticancer, antiviral, antibacterial, anti-inflammatory, antifungal, antifouling, and insecticidal activity have been investigated. This review describes the chemical structures and biological activities of 217 halogenated compounds derived mainly from Penicillium and Aspergillus marine fungal strains reported from 1994 to 2019.

Automated summary

Marine fungi produce a variety of halogenated compounds with diverse structures and biological activities, mainly derived from Penicillium and Aspergillus strains. These compounds have been investigated for their potential pharmaceutical applications, including anticancer, antiviral, antibacterial, anti-inflammatory, antifungal, antifouling, and insecticidal properties.