期刊
MOLECULES
卷 26, 期 2, 页码 -出版社
MDPI
DOI: 10.3390/molecules26020458
关键词
marine fungi; chemical structures; natural products; halogenated compounds
资金
- Guangxi Natural Science Foundation [2019GXNSFBA185002, AD18126005, AD18281066]
- University of Hawaii at Hilo (UHH)
- University of Hawaii Cancer Center (UHCC)
- Daniel K. Inouye College of Pharmacy (DKICP)
- Victoria S. and Bradley L. Geist Foundation [15ADVC-74420, 17CON-86295, 20CON-102163]
- Hawaii IDeA Network for Biomedical Research Excellence III and IV (INBRE-III and INBRE-IV) project: NIGMS [5P20GM103466]
Marine fungi produce a variety of halogenated compounds with diverse structures and biological activities, mainly derived from Penicillium and Aspergillus strains. These compounds have been investigated for their potential pharmaceutical applications, including anticancer, antiviral, antibacterial, anti-inflammatory, antifungal, antifouling, and insecticidal properties.
Marine fungi produce many halogenated metabolites with a variety of structures, from acyclic entities with a simple linear chain to multifaceted polycyclic molecules. Over the past few decades, their pharmaceutical and medical application have been explored and still the door is kept open due to the need of new drugs from relatively underexplored sources. Biological properties of halogenated compounds such as anticancer, antiviral, antibacterial, anti-inflammatory, antifungal, antifouling, and insecticidal activity have been investigated. This review describes the chemical structures and biological activities of 217 halogenated compounds derived mainly from Penicillium and Aspergillus marine fungal strains reported from 1994 to 2019.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据