期刊
MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES
卷 31, 期 4, 页码 628-634出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/13645706.2020.1867584
关键词
Endoscopic intervention; Over-the-scope clip; refractory gastrointestinal disease; prognosis
类别
This study examined the clinical outcomes and long-term characteristics of patients treated with Over-The-Scope Clip (OTSC). The results showed a 100% clinical success rate and a 2.9% complication rate during the observation period. OTSC remains effective in the long-term.
Background: The Over-The-Scope Clip (OTSC) can effectively treat refractory gastrointestinal diseases. However, most reports have focused on short-term effectiveness. We examined clinical outcomes of the deployed clips and long-term characteristics. Material and methods: Of 47 patients with OTSC treatment, 35 with follow-up periods of >= 3 months were retrospectively examined. The indications were 11 bleedings, 17 perforations, and seven fistulas. The observation period was defined as medium-term (3 to <12 months) or long-term (>= 12 months). The primary outcome was the clinical success rate without disease recurrence. The secondary outcomes were the complication rate, survival duration, and clip retention rate. Results: The medium- and long-term clinical success rates were 100% during the observation period (median, 44 months; range, 3-78 months). The complication rate was 2.9% (n = 1). The median survival time was 1,634 days for bleeding, 1,757 days for perforation, and 444 days for fistulas. The overall clip retention rates were 56.4%, 38.1%, 30.9%, and 25.9% after one, six, and 12 months and at the final follow-up, respectively. The average clip retention duration was 244 days in bleeding, 656 days in perforations, and 188 days in fistulas. Conclusions: Regardless of clip detachment, the OTSC can be effective in long-term.
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