Poly(eriochrome black T) modified electrode for electrosensing of methdilazine

The current research work is based on the development of an electrode modified by using an indicator, poly (eriochrome black T) (poly-EBT) for the determination of methdilazine hydrochloride (MDH). Excellent electrocatalytic, semiconducting properties of poly-EBT influences the enhanced peak current of MDH. Different voltammetric techniques like cyclic, square wave voltammetry were employed. The association happens among metallochromic indicators, poly-EBT, and positively charged MDH at the surface of the working electrode. The characterization of poly-EBT modified CPE was studied with the help of atomic force microscopy technique (AFM). The concentration of MDH was determined using poly-EBT modified electrode in the wide concentration range 1.0 x 10(7) M to 0.5 x 10(-4) M with LOD value of 2.57 x 10(-8) M. Poly-EBT modified electrode showed enhanced the sensitivity and selectivity for the determination of MDH in human urine samples and pharmaceutical dosage forms.