Mn-based 2D layered nanomaterials for boosting the MRI signal

Manganese-based 2D nanoparticles with increased longitudinal relaxivity (r(1)) in MRI were synthesised by co-precipitation at low suprasaturation. The results of physico-chemical characterizations, i.e., XRD, FT-IR, DR UV-vis, N-2 physisorption, and SEM, showed an excellent 2D nanomaterial in which manganese is predominantly incorporated as Mn2+ and Mn3+. The r(1) relaxivity obtained on a 1.0 Tesla apparatus at pH = 7.4 is significantly improved (r(1) = 1.298 mM(-1) s(-1)) as compared with other similar layered materials containing manganese. (C) 2021 Elsevier B.V. All rights reserved.

Automated summary

Manganese-based 2D nanoparticles with increased longitudinal relaxivity were synthesized through co-precipitation at low suprasaturation, showing excellent physico-chemical characteristics. The obtained relaxivity on a 1.0 Tesla apparatus at pH = 7.4 is significantly improved compared to other similar materials containing manganese.