Antibacterial activity and in vitro cytotoxicity studies of Ag-doped CaO nanoparticles

CaO nanoparticles can be used in different fields, such as medical and food, some studies suggest that they have poor antimicrobial properties. In this work, CaO nanoparticles doped with different concentrations of Ag were synthesized by the sol-gel method, to improve their antimicrobial activity. Cytotoxicity was also determined by MTT assay. The results of this study showed that it was possible to increase the antimicrobial activity of the CaO nanoparticles by doping them with different concentrations of Ag. According to a cytotoxicity study, a percentage of cell viability above 70% was obtained, thus the nanoparticles of CaO doped with Ag are candidates to be used in medical and food applications. (c) 2020 Elsevier B.V. All rights reserved.

Automated summary

CaO nanoparticles doped with different concentrations of Ag were synthesized by the sol-gel method to enhance their antimicrobial activity. The cytotoxicity study showed a cell viability percentage above 70%, indicating the nanoparticles could be used in medical and food applications.