Facile synthesis of biomass-derived sulfonated carbon microspheres and nanosheets for the electrochemical detection of glutathione in biological samples

Herein, we report a low cost and highly selective electrochemical sensor for the detection of glutathione (GSH) using sulfonated carbon microspheres and nanosheets (SCMN) modified glassy carbon electrode (GCE) with an ultra-low limit of detection of 24.91 pM along with excellent stability and reproducibility. The sensor is successful in the detection of GSH in biological fluids such as blood serum samples with excellent recovery percentages from similar to 92.97 to similar to 101.58%. Thus, SCMN/GCE makes a promising platform for developing low-cost, biocompatible electrodes for biosensing applications. (C) 2020 Elsevier B.V. All rights reserved.

Automated summary

The study presents a low-cost, highly selective electrochemical sensor for detecting glutathione using sulfonated carbon microspheres and nanosheets modified glassy carbon electrode, with an ultra-low limit of detection and excellent stability and reproducibility. The sensor was successful in detecting GSH in biological fluids with excellent recovery percentages, making it a promising platform for developing low-cost, biocompatible electrodes for biosensing applications.