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R Mostoslavsky et al.
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Hepatoprotective constituents of the edible brown alga Ecklonia stolonifera on tacrine-induced cytotoxicity in Hep G2 cells
YC Kim et al.
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Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
E Michishita et al.
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Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation
H Matsuzaki et al.
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D van Heemst et al.
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B Rogina et al.
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M Blüher et al.
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AM Vincent et al.
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M Wagner et al.
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