期刊
LASERS IN MEDICAL SCIENCE
卷 37, 期 1, 页码 225-231出版社
SPRINGER LONDON LTD
DOI: 10.1007/s10103-020-03220-x
关键词
Laser radiation in the green region of the spectrum; Selective photodestruction; Angiodysplasia of skin capillaries; Model objects liver and skin of minipigs; Morphological examination
The selectivity of laser radiation with a wavelength of 525 nm on hemoglobin-containing tissues has been confirmed in experimental studies, showing promise for the selective photothermolysis of pathological subepithelial capillary structures with minimal damage to skin tissues.
To date, the problem of treating pathological subepithelial capillary structures, in particular, capillary angiodysplasia of the skin, remains. One of the promising methods for its elimination is photothermolysis by laser radiation of the yellow-green spectral range due to the selective absorption of blood by hemoglobin in blood vessels and, subsequently, their sclerosis and regression. In experimental work in vitro on model objects, chilled liver and skin samples from minipigs of the Svetlogorsk population, a comparison was made based on morphological studies of the results of the green laser radiation effect with a wavelength of 525 nm on these objects. In the case of a combined object (the liver under the skin), the green laser radiation that is little absorbed by the skin passes through it, which provides an effect on the underlying liver, where more pronounced thermal changes are formed compared to the skin. The results of the experimental study confirmed the selectivity of the laser radiation effect with a wavelength of 525 nm on hemoglobin-containing tissues. This fact is promising for selective photothermolysis of pathological subepithelial capillary structures, which will ensure the precision of treatment with minimal damage to skin tissues.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据