期刊
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
卷 34, 期 6, 页码 604-613出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.echo.2021.01.010
关键词
Fusion imaging; Percutaneous mitral valve repair; 3D echocardiography
This study demonstrated the use of fluoroscopic-echocardiographic fusion imaging for intraprocedural guidance during transcatheter edge-to-edge mitral valve repair, showing a reduction in fluoroscopy time and improvement in procedural success in a population with challenging mitral anatomy for percutaneous repair.
Background: Whether fluoroscopic-echocardiographic fusion imaging (FI) might offer added value for intraprocedural guidance during transcatheter edge-to-edge mitral valve repair is yet unknown, and few data exist regarding the safety and feasibility of this novel technology. Methods: The aim of this single-center study was to test and validate a FI protocol for intraprocedural monitoring of transcatheter edge-to-edge mitral valve repair and assess its clinical usefulness. Eighty patients underwent MitraClip implantation using FI guidance (FI+) for either degenerative (35%) or functional (65%) mitral regurgitation and were compared with the last 80 patients before FI introduction, treated using conventional echocardiography and fluoroscopic monitoring (FI-). Results: The number of patients treated for functional and degenerative mitral regurgitation was similar between the FI+ and FI+ groups, as well as the number of devices implanted (1.51 +/- 0.5 vs 1.58 +/- 0.6, P = .46). The prevalence of complex mitral anatomy for percutaneous repair was high (32.5%, up to 39.2% in the hybrid arm). Fluoroscopy time was significantly lower in FI+ patients (37.3 +/- 14.6 vs 48.3 +/- 28.3 min, P = .003), but not kerma area product (91.5 +/- 74.1 vs 108.8 +/- 105.0 Gy.cm(2), P = .23) or procedural time (92.2 +/- 36.1 vs 103.1 +/- 42.7 min, P = .086). After adjusting for confounding factors (MitraClip XT device and complex anatomy), FI reduced fluoroscopy time (coefficient = -10.4 min; 95% CI, -18.03 to -2.82; P = .007) and improved procedural success at the end of the procedure (odds ratio, 2.87; 95% CI, 1.00 to 8.24; P = .049) and discharge (odds ratio, 2.24; 95% CI, 1.04 to 4.80; P = .039). Rates of periprocedural complications were similar in both groups (8.9% vs 13.0%, P = .40). Conclusions: The authors describe the systematic use of an FI protocol for intraprocedural guidance during transcatheter edge-to-edge mitral valve repair, demonstrating a reduction in fluoroscopy time and an improvement in procedural success in a population with a high prevalence of challenging mitral anatomy for percutaneous repair.
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