4CzIPN-tBu-Catalyzed Proton-Coupled Electron Transfer for Photosynthesis of Phosphorylated N-Heteroaromatics

4,5,6-Tetrakis (3,6-di-tert- butyl-9H-carbazol-9-yl)-isophthalonitrile (4CzIPN-Bu-t) was developed as a photocatalyst for the phosphorus-radical-initiated cascade cyclization reaction of isocyanides. By using 4CzIPN-Bu-t as catalyst, we developed a visiblelight-induced proton-coupled electron transfer strategy for the generation of phosphorus-centered radicals, via which a wide range of phosphorylated phenanthridines, quinolines, and benzothiazoles were successfully constructed.

Automated summary

4,5,6-Tetrakis (3,6-di-tert-butyl-9H-carbazol-9-yl)-isophthalonitrile (4CzIPN-Bu-t) was developed as a photocatalyst for the phosphorus-radical-initiated cascade cyclization reaction of isocyanides. By using 4CzIPN-Bu-t as catalyst, a visible light-induced proton-coupled electron transfer strategy was developed for the generation of phosphorus-centered radicals, leading to the successful construction of phosphorylated phenanthridines, quinolines, and benzothiazoles.