4.4 Article

Frailty as a predictor of disabilities among community-dwelling older people: a systematic review and meta-analysis

期刊

DISABILITY AND REHABILITATION
卷 39, 期 19, 页码 1897-1908

出版社

TAYLOR & FRANCIS LTD
DOI: 10.1080/09638288.2016.1212282

关键词

Frailty; disability; activities of daily living; instrumental activities of daily living; community-dwelling older people

向作者/读者索取更多资源

Background: Frailty has been shown to be associated with disability in the previous studies. However, it is not clear how consistently or to how much degree frailty is actually associated with the future disability risks. Methods: A systematic review of the literature was conducted using Embase, MEDLINE, CINAHL, PsycINFO, and the Cochrane Library for any prospective studies published from 2010 to September 2015 examining associations between baseline frailty status and subsequent risk of developing or worsening disabilities among community-dwelling older people. A meta-analysis was performed to synthesize pooled estimates. Results: Of 7012 studies identified through the systematic review, 20 studies were included in the meta-analysis. Twelve studies examined activities of daily living (ADL) disability risks, two studies examined instrumental activities of daily living (IADL) disability risks, and six studies examined both ADL and IADL disability risks. Overall, frail older people were more likely to develop or worsen disabilities in ADL (12 studies, pooled OR=2.76, 95% CI=2.23-3.44, p<0.00001; 5 studies, pooled HR=2.23, 95% CI=1.42-3.49, p<0.00001) and IADL (6 studies, pooled OR=3.62, 95% CI=2.32-5.64, p<0.00001; 2 studies, pooled HR=4.24, 95% CI=0.85-21.28, p=0.08). Prefrailty was also associated with incident or worsening disability risks to a lesser degree in most pooled analyses. High heterogeneity observed among 12 studies with OR of ADL disability risks for frailty was explored using subgroup analyses, which suggested methodological quality and mean age of the cohort were the possible causes. Conclusion: This systematic review meta-analysis quantitatively showed that frail older people are at higher risks of disabilities. These results are important for all related parties given population aging worldwide. Interventions for frailty are important to prevent disability and preserve physical functions, autonomy, and quality of life.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.4
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据