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My 60-Year Love Affair with Natural Products

期刊

JOURNAL OF NATURAL PRODUCTS
卷 84, 期 3, 页码 932-948

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acs.jnatprod.0c01237

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资金

  1. National Institutes of Health [CA12831, CA 23857, CA 40771, CA 48974, CA 55131, TW00313, CA69571, AT008088]
  2. National Science Foundation [PCM-89111508]
  3. American Cancer Society [CH268]
  4. SmithKline Animal Health Products
  5. Bristol-Myers Squibb

向作者/读者索取更多资源

The author discusses his 60-year career in studying the chemistry of natural products, including structural, synthetic, and biosynthetic studies of various natural products like insect pigments, antibiotics, fecal mutagens, taxol, anticancer drugs, and antimalarial drugs. One compound, napabucasin, is highlighted as now being in phase III clinical trials as an anticancer drug.
The author describes his 60-year career in studying the chemistry of natural products, which includes structural, synthetic, and biosynthetic studies of natural products ranging from insect pigments, antibiotics, and fecal mutagens to taxol and other anticancer natural products as well as antimalarial natural products. One of the compounds discussed, napabucasin, is now an anticancer drug in phase III clinical trials.

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