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Kamila Buzun et al.
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Xiaoxia Liang et al.
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Peichen Pang et al.
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Design and Synthesis of Chlorinated and Fluorinated 7-Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I
Mohamed S. A. Elsayed et al.
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Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl-DNA Phosphodiesterase 2 (Tdp2)
Ping Wang et al.
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Bistratamides M and N, Oxazole-Thiazole Containing Cyclic Hexapeptides Isolated from Lissoclinum bistratum Interaction of Zinc (II) with Bistratamide K
Carlos Urda et al.
MARINE DRUGS (2017)
Investigation of the Structure-Activity Relationships of Aza-A-Ring Indenoisoquinoline Topoisomerase I Poisons
Daniel E. Beck et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Design, Synthesis, and Biological Evaluation of Potential Prodrugs Related to the Experimental Anticancer Agent Indotecan (LMP400)
Peng-Cheng Lv et al.
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Access to Indole-Fused Polyheterocycles via Pd-Catalyzed Base-Free Intramolecular Cross Dehydrogenative Coupling
Chao Cheng et al.
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Nurul H. Ansari et al.
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Radical Beckmann Rearrangement and Its Application in the Formal Total Synthesis of Antimalarial Natural Product Isocryptolepine via C-H Activation
Pankaj S. Mahajan et al.
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Pasuk Aroonkit et al.
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Environmentally benign synthesis of 4-aminoquinoline-2-ones using recyclable choline hydroxide
Anita Kailas Sanap et al.
NEW JOURNAL OF CHEMISTRY (2015)
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Yu-Chieh Lee et al.
PLOS ONE (2015)
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Ning Wang et al.
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Synthesis and in vitro cytotoxic effect of 6-amino-substituted 11H- and 11Me-indolo[3,2-c]quinolines
Ning Wang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Synthesis of Polysubstituted Phenanthridines via Ligand-Free Copper-Catalyzed Annulation
Yan-Fu Chen et al.
ORGANIC LETTERS (2014)
Regioselective N-Methylation of 6-Chloroindolo[3,2-c]quinolines and Their Amination Reactivity at the C-6 Position
Ning Wang et al.
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN (2013)
Synthesis of Diversely Substituted Indoloquinolinones via Pd(II)/Cu(II)-Mediated Oxidative C-C Bond Formation and I(III)-Mediated C-N Bond Formation
Xiang Zhang et al.
JOURNAL OF ORGANIC CHEMISTRY (2013)
Quadri-Synergetic Effect for Highly Effective Carbon Dioxide Fixation and Its Application to Indoloquinolinone
Suhua Li et al.
ADVANCED SYNTHESIS & CATALYSIS (2012)
Identification, Synthesis, and Biological Evaluation of Metabolites of the Experimental Cancer Treatment Drugs Indotecan (LMP400) and Indimitecan (LMP776) and Investigation of Isomerically Hydroxylated Indenoisoquinoline Analogues as Topoisomerase I Poisons
Mans A. Cinelli et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
A novel total synthesis of isocryptolepine based on a microwave-assisted tandem Curtius rearrangement and aza-electrocyclic reaction
Kaori Hayashi et al.
TETRAHEDRON (2012)
Synthesis and antimalarial evaluation of novel isocryptolepine derivatives
Louise R. Whittell et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Genz-644282, a Novel Non-Camptothecin Topoisomerase I Inhibitor for Cancer Treatment
Leslie S. Kurtzberg et al.
CLINICAL CANCER RESEARCH (2011)
Topoisomerase I expression in tumors as a biological marker for CPT-11 chemosensitivity in patients with colorectal cancer
Masahide Ikeguchi et al.
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Synthesis and antiproliferative evaluation of certain indolo[3,2-c]quinoline derivatives
Chih-Ming Lu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
CuI-catalyzed photochemical or thermal reactions of 3-(2-azidobenzylidene)lactams. Application to the synthesis of fused indoles
Zongjun Shi et al.
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Structure-Activity Relationships of Highly Cytotoxic Copper(II) Complexes with Modified Indolo[3,2-c]quinoline Ligands
Michael F. Primik et al.
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Discovery of Pyrrole-Indoline-2-ones as Aurora Kinase Inhibitors with a Different Inhibition Profile
Chao-Cheng Chiang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
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Yves Pommier
CHEMICAL REVIEWS (2009)
AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility
Garrett M. Morris et al.
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Lewis Acid Catalyzed Indole Synthesis via Intramolecular Nucleophilic Attack of Phenyldiazoacetates to Iminium Ions
Lei Zhou et al.
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Novel indenoisoquinolines NSC 725776 and NSC 724998 produce persistent topolsomerase I cleavage complexes and overcome multidrug resistance
Smitha Antony et al.
CANCER RESEARCH (2007)
The NCI60 human tumour cell line anticancer drug screen
Robert H. Shoemaker
NATURE REVIEWS CANCER (2006)
Topoisomerase I inhibitors: camptothecins and beyond
Yves Pommier
NATURE REVIEWS CANCER (2006)
Synthesis and mechanism of action studies of a series of norindenoisoquinoline topoisomerase I poisons reveal an inhibitor with a flipped orientation in the ternary DNA-enzyme-inhibitor complex as determined by X-ray crystallographic analysis
A Ioanoviciu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Mechanisms of resistance to topoisomerase I-targeting drugs
ZA Rasheed et al.
ONCOGENE (2003)
5H-Dibenzo[c,h]1,6-naphthyridin-6-ones:: Novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity
AL Ruchelman et al.
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Studies of the reactions between indole-2,3-diones (isatins) and 2-aminobenzylamine
J Bergman et al.
TETRAHEDRON (2003)
Design of antineoplastic agents based on the '2-phenylnaphthalene-type' structural pattern - synthesis and biological activity studies of 11H-indolo[3.2-c]quinoline derivatives
L He et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2003)
The mechanism of topoisomerase I poisoning by a camptothecin analog
BL Staker et al.
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Diaza- and triazachrysenes: Potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435
AL Ruchelman et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2002)
Synthesis and cytotoxic activity evaluation of indolo-, pyrrolo-, and benzofuro-quinolin-2(1H)-ones and 6-anilinoindoloquinoline derivatives
YL Chen et al.
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Cellular roles of DNA topoisomerases: A molecular perspective
JC Wang
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
A novel approach to the indoloquinoline alkaloids cryptotackieine and cryptosanguinolentine by application of cyclization of o-vinylsubstituted arylheterocumulenes
PM Fresneda et al.
TETRAHEDRON (2001)
Expression of DNA topoisomerase I in neoplasms of the kidney: Correlation with histological grade, proliferation, and patient survival
D Gupta et al.
HUMAN PATHOLOGY (2000)
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