4.3 Article

Research guidelines for embryoids

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JOURNAL OF MEDICAL ETHICS
卷 47, 期 12, 页码 -

出版社

BMJ PUBLISHING GROUP
DOI: 10.1136/medethics-2020-106493

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public policy; research ethics; stem cell research

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Human embryo models formed from stem cells, known as embryoids, are valuable for studying early stages of development without the need for experimenting on real human embryos. However, clear ethical guidelines are still lacking for research involving embryoids. Some researchers have proposed new recommendations for embryoids, but these recommendations are not feasible as they rely on a concept of 'potential' that triggers strict research regulations.
Human embryo models formed from stem cells-known as embryoids-allow scientists to study the elusive first stages of human development without having to experiment on actual human embryos. But clear ethical guidelines for research involving embryoids are still lacking. Previously, a handful of researchers put forward new recommendations for embryoids, which they hope will be included in the next set of International Society for Stem Cell Research guidelines. Although these recommendations are an improvement over the default approach, they are nonetheless unworkable, because they rely on a poorly conceived notion of an embryoid's 'potential' to trigger stringent research regulations.

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