期刊
JOURNAL OF INFECTIOUS DISEASES
卷 224, 期 1, 页码 133-136出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/infdis/jiaa715
关键词
rotavirus; vaccine; cohort; IgG; immunity; maternal antibodies
资金
- US Centers for Disease Control and Prevention [IP16-004]
Rotavirus-specific antibodies continue to be transferred from US mothers to their offspring in the post-rotavirus vaccine era, despite significant decreases in childhood rotavirus gastroenteritis.
To assess whether titers of anti-rotavirus immunoglobulin G persist during the post-rotavirus vaccine era, the Pediatric Respiratory and Enteric Virus Acquisition and Immunogenesis Longitudinal (PREVAIL) Cohort analyzed serum samples collected from Cincinnati-area mothers and young infants in 2017-2018. Rotavirus-specific antibodies continue to be transferred from US mothers to their offspring in the post-rotavirus vaccine era, despite dramatic decreases in childhood rotavirus gastroenteritis.
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