Telogen Effluvium - a review of the science and current obstacles

Telogen effluvium (TE) is a common cause of diffuse non-scarring hair loss that is usually precipitated by physiological stress such as childbirth or sudden weight loss. Despite its high rate of remission, this phenomenon of sudden excessive hair loss can be very worrisome and upsetting for affected individuals and may significantly impact their quality of life. Due to the multifactorial causes and precipitants of TE, it is often challenging to diagnose and manage. Further, the mechanisms through which physiological stress influences the human hair cycle is unknown, and there are no targeted treatments for the management of TE. This review will describe the approach in making a diagnosis of TE, summarize the latest developments made in understanding the mechanisms of TE, outline the treatments tried, and recommend ways for advancing the study of this dermatological condition. (C) 2021 Published by Elsevier B.V. on behalf of Japanese Society for Investigative Dermatology.

Automated summary

Telogen effluvium is a common cause of non-scarring hair loss, usually triggered by physiological stress like childbirth or sudden weight loss. Despite having a high rate of remission, it can still be very concerning and upsetting for individuals affected. Due to its multifactorial causes and triggers, diagnosising and managing TE is often challenging.