In vitro activity of dalbavancin against biofilms of staphylococci isolated from prosthetic joint infections

The in vitro activity of dalbavancin was tested against biofilms of 171 staphylococci associated with prosthetic joint infection. Dalbavancin minimum biofilm bactericidal concentration (MBBC) values were: MBBC50 for Staphylococcus aureus and Staphylococcus epidermidis, 1 mu g/mL; MBBC90 for S. aureus, 2 mu g/mL; MBBC90 for S. epidermidis, 4 mu g/mL. (C) 2016 Elsevier Inc. All rights reserved.