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Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs
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JOURNAL OF MOLECULAR ENDOCRINOLOGY (2019)
The Role of Sirt6 in Obesity and Diabetes
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FRONTIERS IN PHYSIOLOGY (2018)
Coordinate regulation by transcription factors and DNA methylation in the core promoter region of SIRT6 in bovine adipocytes
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ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2018)
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TRENDS IN ENDOCRINOLOGY AND METABOLISM (2017)
The Metabolic Memory Theory and the Early Treatment of Hyperglycemia in Prevention of Diabetic Complications
Roberto Testa et al.
NUTRIENTS (2017)
Sirtuin 6, a possible therapeutic target for type 2 diabetes
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5-Hydroxymethylcytosine-mediated alteration of transposon activity associated with the exposure to adverse in utero environments in human
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HUMAN MOLECULAR GENETICS (2016)
Dynamic DNA methylation of matrix metalloproteinase-9 in the development of diabetic retinopathy
Renu A. Kowluru et al.
LABORATORY INVESTIGATION (2016)
The role of global and regional DNA methylation and histone modifications in glycemic traits and type 2 diabetes: A systematic review
T. Muka et al.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2016)
ITCH modulates SIRT6 and SREBP2 to influence lipid metabolism and atherosclerosis in ApoE null mice
R. Stoehr et al.
SCIENTIFIC REPORTS (2015)
Enhanced insulin sensitivity in skeletal muscle and liver by physiological overexpression of SIRT6
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MOLECULAR METABOLISM (2015)
Sirtuin 6 Expression and Inflammatory Activity in Diabetic Atherosclerotic Plaques: Effects of Incretin Treatment
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Site Kugel et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Effects of hyperglycemia and aging on nuclear sirtuins and DNA damage of mouse hepatocytes
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MOLECULAR BIOLOGY OF THE CELL (2013)
TET enzymes, TDG and the dynamics of DNA demethylation
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NATURE (2013)
Metabolic Memory and Chronic Diabetes Complications: Potential Role for Epigenetic Mechanisms
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CURRENT DIABETES REPORTS (2012)
Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
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SCIENCE (2011)
The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
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Metabolic memory and diabetic nephropathy: potential role for epigenetic mechanisms
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NATURE REVIEWS NEPHROLOGY (2010)
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
Ronald A. McCord et al.
AGING-US (2009)
SIRT6 in DNA repair, metabolism and ageing
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JOURNAL OF INTERNAL MEDICINE (2008)
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
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CELL (2006)
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