期刊
JOURNAL OF BIOPHOTONICS
卷 14, 期 3, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jbio.202000370
关键词
biomedical imaging; co‐ registration; digital subtraction angiography; intravascular imaging; optical coherence tomography; three‐ dimensional spatial reconstruction
资金
- National Instrumentation Program [2013YQ030915]
- China Postdoctoral Science Foundation [2015M580199, 2016T90205]
- National Key Research and Development Program [2019YFC0120701, 2019YFC0120703]
- National Natural Science Foundation of China [61505138, 61635008, 61735011, 61975147]
- Tianjin Science and Technology Support Plan Program Funding [16JCQNJC01800]
A three-dimensional spatial reconstruction of coronary arteries based on fusion of IVOCT and DSA was presented, extracting vessel centerline from DSA images and matching lumen shapes between IVOCT and DSA images. The models showed a high level of matching, with a correlation coefficient of 0.94% and 97.7% falling within the limit of agreement by Bland-Altman analysis.
We present a three-dimensional (3D) spatial reconstruction of coronary arteries based on fusion of intravascular optical coherence tomography (IVOCT) and digital subtraction angiography (DSA). Centerline of vessel in DSA images is exacted by multi-scale filtering, adaptive segmentation, morphology thinning and Dijkstra's shortest path algorithm. We apply the cross-correction between lumen shapes of IVOCT and DSA images and match their stenosis positions to realize co-registration. By matching the location and tangent direction of the vessel centerline of DSA images and segmented lumen coordinates of IVOCT along pullback path, 3D spatial models of vessel lumen are reconstructed. Using 1121 distinct positions selected from eight vessels, the correlation coefficient between 3D IVOCT model and DSA image in measuring lumen radius is 0.94% and 97.7% of the positions fall within the limit of agreement by Bland-Altman analysis, which means that the 3D spatial reconstruction IVOCT models and DSA images have high matching level.
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