相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Using Machine Learning Methods and Structural Alerts for Prediction of Mitochondrial Toxicity
Jennifer Hemmerich et al.
MOLECULAR INFORMATICS (2020)
Orexin-A exacerbates Alzheimer's disease by inducing mitochondrial impairment
Maoyu Li et al.
NEUROSCIENCE LETTERS (2020)
Ring-Substituted 1-Hydroxynaphthalene-2-Carboxanilides Inhibit Proliferation and Trigger Mitochondria-Mediated Apoptosis
Tereza Kauerova et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Mitochondria and T2D: Role of Autophagy, ER Stress, and Inflammasome
Milagros Rocha et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2020)
Discriminant models on mitochondrial toxicity improved by consensus modeling and resolving imbalance in training
Weihao Tang et al.
CHEMOSPHERE (2020)
Aldehyde toxicity and metabolism: the role of aldehyde dehydrogenases in detoxification, drug resistance and carcinogenesis
Amaj Ahmed Laskar et al.
DRUG METABOLISM REVIEWS (2019)
The potential role of mitochondrial impairment in the pathogenesis of imatinib-induced renal injury
Ehsan Emadi et al.
HELIYON (2019)
Drug-Induced Mitochondrial Toxicity in the Geriatric Population: Challenges and Future Directions
Yvonne Will et al.
BIOLOGY-BASEL (2019)
DrugBank 5.0: a major update to the DrugBank database for 2018
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2018)
In silico estimation of chemical aquatic toxicity on crustaceans using chemical category methods
Qianqian Cao et al.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS (2018)
Improving the accuracy of k-nearest neighbor using local mean based and distance weight
K. U. Syaliman et al.
2ND INTERNATIONAL CONFERENCE ON COMPUTING AND APPLIED INFORMATICS 2017 (2018)
Development of novel prediction model for drug-induced mitochondrial toxicity by using naive Bayes classifier method
Hui Zhang et al.
FOOD AND CHEMICAL TOXICOLOGY (2017)
The use of high-throughput screening techniques to evaluate mitochondrial toxicity
Lauren P. Wills
TOXICOLOGY (2017)
Efficiency of different measures for defining the applicability domain of classification models
Waldemar Klingspohn et al.
JOURNAL OF CHEMINFORMATICS (2017)
Evaluation of Different Methods for Identification of Structural Alerts Using Chemical Ames Mutagenicity Data Set as a Benchmark
Hongbin Yang et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2017)
Drug-Induced Mitochondrial Toxicity
Iain P. Hargreaves et al.
DRUG SAFETY (2016)
TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions
Inmaculada Martinez-Reyes et al.
MOLECULAR CELL (2016)
Chemoinformatic Classification Methods and their Applicability Domain
Miriam Mathea et al.
MOLECULAR INFORMATICS (2016)
Mitochondrial toxicity of diclofenac and its metabolites via inhibition of oxidative phosphorylation (ATP synthesis) in rat liver mitochondria: Possible role in drug induced liver injury (DILI)
Muzeeb Syed et al.
TOXICOLOGY IN VITRO (2016)
Feature Selection Using Information Gain for Improved Structural-Based Alert Correlation
Taqwa Ahmed Alhaj et al.
PLOS ONE (2016)
Development of an in Silico Profiler for Mitochondrial Toxicity
Mark D. Nelms et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2015)
Targeting mitochondria metabolism for cancer therapy
Samuel E. Weinberg et al.
NATURE CHEMICAL BIOLOGY (2015)
Mitochondrial toxicity assessment in industry - a decade of technology development and insight
Yvonne Will et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2014)
Computational Derivation of Structural Alerts from Large Toxicology Data Sets
Ernst Ahlberg et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2014)
Mechanisms of nanotoxicity: Generation of reactive oxygen species
Peter P. Fu et al.
JOURNAL OF FOOD AND DRUG ANALYSIS (2014)
Boosting: Foundations and Algorithms20131Boosting: Foundations and Algorithms. The MIT Press, 2012. xv +526 pp. Cloth, $50.00 or £34.95, ISBN: ‐10: 0‐262‐01718‐0; ‐13: 978‐0‐262‐01718‐3
Robert E. Schapire
KYBERNETES (2014)
Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition
Sunita Maharjan et al.
SCIENTIFIC REPORTS (2014)
Complex I impairment in mitochondrial diseases and cancer: Parallel roads leading to different outcomes
Luisa Iommarini et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
Automatic knowledge extraction from chemical structures: the case of mutagenicity prediction
T. Ferrari et al.
SAR AND QSAR IN ENVIRONMENTAL RESEARCH (2013)
Mitochondria as a Target of Environmental Toxicants
Joel N. Meyer et al.
TOXICOLOGICAL SCIENCES (2013)
The Maintenance of Mitochondrial DNA Integrity-Critical Analysis and Update
Mikhail Alexeyev et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Cellular and molecular mechanisms of mitochondrial function
Laura D. Osellame et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Mechanistic understanding of drug-induced mitochondrial toxicity using isolated mitochondrial complex assays
Emma L. Low et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2012)
PaDEL-Descriptor: An Open Source Software to Calculate Molecular Descriptors and Fingerprints
Chun Wei Yap
JOURNAL OF COMPUTATIONAL CHEMISTRY (2011)
Bioenergetics and cell death
Yulia Kushnareva et al.
MITOCHONDRIAL RESEARCH IN TRANSLATIONAL MEDICINE (2010)
Estimation of ADME Properties with Substructure Pattern Recognition
Jie Shen et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)
Replacement, reduction and refinement alternatives to animal use in vaccine potency measurement
Coenraad F. M. Hendriksen
EXPERT REVIEW OF VACCINES (2009)
In silico prediction of mitochondrial toxicity by using GA-CG-SVM approach
Hui Zhang et al.
TOXICOLOGY IN VITRO (2009)
Medication-induced mitochondrial damage and disease
John Neustadt et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2008)
Co-oxidation-mediated xenobiotic activation and cytotoxicity by 12-lipoxygenase in intact platelets
Kyung-Min Lim et al.
TOXICOLOGY (2008)
In silico prediction of cytochrome P450 2D6 and 3A4 inhibition using Gaussian kernel weighted k-nearest neighbor and extended connectivity fingerprints, including structural fragment analysis of inhibitors versus noninhibitors
Berith F. Jensen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Mitochondria: Dynamic organelles in disease, aging, and development
David C. Chan
CELL (2006)
Mitochondrial cytopathy in adults: What we know so far
BH Cohen et al.
CLEVELAND CLINIC JOURNAL OF MEDICINE (2001)
分享论文
