4.3 Article

Steroid-induced rapid recovery from respiratory dysfunction in a patient with myasthenia gravis after spinal anesthesia

期刊

JOURNAL OF ANESTHESIA
卷 35, 期 1, 页码 142-144

出版社

SPRINGER JAPAN KK
DOI: 10.1007/s00540-020-02874-9

关键词

Steroid; Non-genomic effects; Spinal anesthesia; Respiratory failure; Myasthenia gravis

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An 83-year-old man with MG developed respiratory depression after spinal anesthesia, but his condition improved after treatment. The surgery was completed successfully and the patient was discharged without any respiratory problems on postoperative day 3.
We report an 83-year-old man with myasthenia gravis (MG) who developed respiratory depression after spinal anesthesia for transurethral laser enucleation of the prostate. He became less responsive after complained of dyspnea, with a decrease of SpO(2) to 83% approximately 13 min after intrathecal administration of 0.5% isobaric bupivacaine 3 ml. With a diagnosis of exacerbation of MG, hydrocortisone 100 mg was administered, following which both consciousness and spontaneous respiration rapidly improved. Cold sense was observed below the C4 dermatome. We provided general anesthesia without using muscle relaxants until disappearance of the effect of spinal anesthesia. Surgery completed uneventfully and confirmed wearing off the local anesthetics effect. He was discharged without respiratory problems on postoperative 3 day.

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