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JOURNAL OF CLINICAL ONCOLOGY (2020)
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LANCET ONCOLOGY (2020)
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
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JOURNAL OF CLINICAL ONCOLOGY (2019)
EV-201: Results of enfortumab vedotin monotherapy for locally advanced or metastatic urothelial cancer previously treated with platinum and immune checkpoint inhibitors.
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JOURNAL OF CLINICAL ONCOLOGY (2019)
Erdafitinib in Locally Advanced or Metastatic Urothelial Carcinoma
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NEW ENGLAND JOURNAL OF MEDICINE (2019)
Management of Urothelial Bladder Cancer in Clinical Practice: Real-world Answers to Difficult Questions
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JOURNAL OF ONCOLOGY PRACTICE (2019)
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ANNALS OF ONCOLOGY (2019)
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ONCOLOGY REPORTS (2019)
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ANNALS OF ONCOLOGY (2018)
Phase II trial of afatinib in patients with advanced/metastatic urothelial carcinoma (UC) with genetic alterations in ERBB receptors 1-3 who failed on platinum-based chemotherapy (CT).
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JOURNAL OF CLINICAL ONCOLOGY (2018)
Molecular Characterization of Urothelial Carcinoma of the Bladder and Upper Urinary Tract
Ji Yun Lee et al.
TRANSLATIONAL ONCOLOGY (2018)
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CANCER DISCOVERY (2018)
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CA-A CANCER JOURNAL FOR CLINICIANS (2018)
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PHARMACOLOGICAL RESEARCH (2018)
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BIOCHEMICAL SOCIETY TRANSACTIONS (2018)
Matriptase-Induced Phosphorylation of MET is Significantly Associated with Poor Prognosis in Invasive Bladder Cancer; an Immunohistochemical Analysis
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Known and novel roles of the MET oncogene in cancer: a coherent approach to targeted therapy
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A Phase II Trial of Dovitinib in BCG-Unresponsive Urothelial Carcinoma with FGFR3 Mutations or Overexpression: Hoosier Cancer Research Network Trial HCRN 12-157
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CLINICAL CANCER RESEARCH (2017)
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EUROPEAN UROLOGY (2017)
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ONCOTARGET (2017)
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NATURE REVIEWS DISEASE PRIMERS (2017)
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Therapeutics Targeting FGF Signaling Network in Human Diseases
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SUCCINCT: An Open-label, Single-arm, Non-randomised, Phase 2 Trial of Gemcitabine and Cisplatin Chemotherapy in Combination with Sunitinib as First-line Treatment for Patients with Advanced Urothelial Carcinoma
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NOTCH pathway inactivation promotes bladder cancer progression
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Gopa Iyer et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
Complexity of FGFR signalling in metastatic urothelial cancer
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JOURNAL OF HEMATOLOGY & ONCOLOGY (2015)
The Role of EGFR Family Inhibitors in Muscle Invasive Bladder Cancer: A Review of Clinical Data and Molecular Evidence
Benjamin A. Mooso et al.
JOURNAL OF UROLOGY (2015)
Second-Line Treatment of Advanced Urothelial Cancer with Paclitaxel and Everolimus in a German Phase II Trial (AUO Trial AB 35/09)
Guenter Niegisch et al.
ONCOLOGY (2015)
PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex
Pengda Liu et al.
CANCER DISCOVERY (2015)
The Fibroblast Growth Factor signaling pathway
David M. Ornitz et al.
WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY (2015)
NOTCH Decoys That Selectively Block DLL/NOTCH or JAG/NOTCH Disrupt Angiogenesis by Unique Mechanisms to Inhibit Tumor Growth
Thaned Kangsamaksin et al.
CANCER DISCOVERY (2015)
Bladder cancer: ESMO Practice Guidelines for diagnosis, treatment and follow-up
J. Bellmunt et al.
ANNALS OF ONCOLOGY (2014)
Prognostic role of FGFR1 amplification in early-stage non-small cell lung cancer
N. Cihoric et al.
BRITISH JOURNAL OF CANCER (2014)
Double-Blind, Randomized, Phase 2 Trial of Maintenance Sunitinib Versus Placebo After Response to Chemotherapy in Patients With Advanced Urothelial Carcinoma
Petros D. Grivas et al.
CANCER (2014)
A Randomized Phase 2 Trial of Gemcitabine/Cisplatin With or Without Cetuximab in Patients With Advanced Urothelial Carcinoma
Maha Hussain et al.
CANCER (2014)
A High Frequency of Activating Extracellular Domain ERBB2 (HER2) Mutation in Micropapillary Urothelial Carcinoma
Jeffrey S. Ross et al.
CLINICAL CANCER RESEARCH (2014)
Phase 2 trial of dovitinib in patients with progressive FGFR3-mutated or FGFR3 wild-type advanced urothelial carcinoma
Matthew I. Milowsky et al.
EUROPEAN JOURNAL OF CANCER (2014)
Tumor infiltrating B-cells are increased in prostate cancer tissue
Jason R. Woo et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2014)
Identification of ALK Gene Alterations in Urothelial Carcinoma
Joaquim Bellmunt et al.
PLOS ONE (2014)
Reduced membranous MET expression is linked to bladder cancer progression
Martina Kluth et al.
CANCER GENETICS (2014)
Combined treatment with pazopanib and vinflunine in patients with advanced urothelial carcinoma refractory after first-line therapy
Holger Gerullis et al.
ANTI-CANCER DRUGS (2013)
Phase II study of everolimus in metastatic urothelial cancer
Matthew I. Milowsky et al.
BJU INTERNATIONAL (2013)
A Phase II Safety and Efficacy Study of the Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor Pazopanib in Patients With Metastatic Urothelial Cancer
Roberto Pili et al.
CLINICAL GENITOURINARY CANCER (2013)
The Down-Regulation of Notch1 Inhibits the Invasion and Migration of Hepatocellular Carcinoma Cells by Inactivating the Cyclooxygenase-2/Snail/E-cadherin Pathway In Vitro
Liang Zhou et al.
DIGESTIVE DISEASES AND SCIENCES (2013)
Phase II Study of Gemcitabine, Carboplatin, and Bevacizumab in Patients With Advanced Unresectable or Metastatic Urothelial Cancer
Arjun V. Balar et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
Tumour cell responses to new fibroblast growth factor receptor tyrosine kinase inhibitors and identification of a gatekeeper mutation in FGFR3 as a mechanism of acquired resistance
V. Chell et al.
ONCOGENE (2013)
Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial tract: clinical activity, molecular response, and biomarkers
E. Seront et al.
ANNALS OF ONCOLOGY (2012)
Mutations increased overexpression of Notch1 in T-cell acute lymphoblastic leukemia
Chunlan Lin et al.
CANCER CELL INTERNATIONAL (2012)
Bruton Tyrosine Kinase (BTK) and Its Role in B-cell Malignancy
Joseph J. Buggy et al.
INTERNATIONAL REVIEWS OF IMMUNOLOGY (2012)
Phase II Trial of Cetuximab With or Without Paclitaxel in Patients With Advanced Urothelial Tract Carcinoma
Yu-Ning Wong et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Neoadjuvant chemotherapy with DD-MVAC and bevacizumab in high-risk urothelial cancer: Results from a phase II trial at the M. D. Anderson Cancer Center
Arlene O. Siefker-Radtke et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Accuracy of HER2 status determination on breast core-needle biopsies (immunohistochemistry, FISH, CISH and SISH vs FISH)
Laurent Arnouldi et al.
MODERN PATHOLOGY (2012)
Pazopanib in advanced and platinum-resistant urothelial cancer: an open-label, single group, phase 2 trial
Andrea Necchi et al.
LANCET ONCOLOGY (2012)
Coexpression of SGLT1 and EGFR is associated with tumor differentiation in oral squamous cell carcinoma
Yasuko Hanabata et al.
ODONTOLOGY (2012)
Fra-1 controls motility of bladder cancer cells via transcriptional upregulation of the receptor tyrosine kinase AXL
A. E. Sayan et al.
ONCOGENE (2012)
Genome Sequencing Identifies a Basis for Everolimus Sensitivity
Gopa Iyer et al.
SCIENCE (2012)
ALK signaling and target therapy in anaplastic large cell lymphoma
Fabrizio Tabbo et al.
FRONTIERS IN ONCOLOGY (2012)
Phase II study of sunitinib as first-line treatment of urothelial cancer patients ineligible to receive cisplatin-based chemotherapy: baseline interleukin-8 and tumor contrast enhancement as potential predictive factors of activity
J. Bellmunt et al.
ANNALS OF ONCOLOGY (2011)
Germline Gain-of-Function Mutations of ALK Disrupt Central Nervous System Development
Loic de Pontual et al.
HUMAN MUTATION (2011)
Molecular control of endothelial cell behaviour during blood vessel morphogenesis
Shane P. Herbert et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
Michelle C. Mendoza et al.
TRENDS IN BIOCHEMICAL SCIENCES (2011)
Results of the Southwest Oncology Group phase II evaluation (study S0031) of ZD1839 for advanced transitional cell carcinoma of the urothelium
Daniel P. Petrylak et al.
BJU INTERNATIONAL (2010)
EGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activity
Hu Zhu et al.
CANCER LETTERS (2010)
Cross-talk between miRNA and Notch signaling pathways in tumor development and progression
Zhiwei Wang et al.
CANCER LETTERS (2010)
Phase II Study of Sunitinib in Patients With Metastatic Urothelial Cancer
David J. Gallagher et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus
Longfei Huo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Phase II Study of Aflibercept (VEGF-Trap) in Patients With Recurrent or Metastatic Urothelial Cancer, a California Cancer Consortium Trial
Przemyslaw Twardowski et al.
UROLOGY (2010)
A phase II trial of cisplatin (C), gemcitabine (G) and gefitinib for advanced urothelial tract carcinoma: results of Cancer and Leukemia Group B (CALGB) 90102
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ANNALS OF ONCOLOGY (2009)
A Single-arm, Multicenter, Open-label Phase 2 Study of Lapatinib as the Second-line Treatment of Patients With Locally Advanced or Metastatic Transitional Cell Carcinoma
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CANCER (2009)
Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL
Li Liu et al.
CANCER RESEARCH (2009)
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
Raphael Kopan et al.
CELL (2009)
Large-scale Real-time Reverse Transcription-PCR Approach of Angiogenic Pathways in Human Transitional Cell Carcinoma of the Bladder: Identification of VEGFA as a Major Independent Prognostic Marker
Geraldine Pignot et al.
EUROPEAN UROLOGY (2009)
The aggressiveness of urothelial carcinoma depends to a large extent on lymphovascular invasion - the prognostic contribution of related molecular markers
Julieta Afonso et al.
HISTOPATHOLOGY (2009)
Phosphorylated hepatocyte growth factor receptor/c-Met is associated with tumor growth and prognosis in patients with bladder cancer: correlation with matrix metalloproteinase-2 and-7 and E-cadherin
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HUMAN PATHOLOGY (2009)
Clinical Features and Outcome of Patients With Non-Small-Cell Lung Cancer Who Harbor EML4-ALK
Alice T. Shaw et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Induction of ERBB2 Nuclear Transport after Radiation in Breast Cancer Cells
Bo Luo et al.
JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES (2009)
Receptor tyrosine kinase AXL is induced by chemotherapy drugs and overexpression of AXL confers drug resistance in acute myeloid leukemia
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CANCER LETTERS (2008)
Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression
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NUCLEIC ACIDS RESEARCH (2008)
The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus
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CANCER RESEARCH (2007)
Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma:: Results of a multicenter phase II National Cancer Institute trial
Maha H. A. Hussain et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Tyrosine phosphorylation controls PCNA function through protein stability
Shao-Chun Wang et al.
NATURE CELL BIOLOGY (2006)
Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival
HW Lo et al.
BRITISH JOURNAL OF CANCER (2006)
Notch signalling: a simple pathway becomes complex
Sarah J. Bray
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Multiple roles for the receptor tyrosine kinase Axl in tumor formation
SJ Holland et al.
CANCER RESEARCH (2005)
Altered ErbB receptor signaling and gene expression in cisplatin-resistant ovarian cancer
K Macleod et al.
CANCER RESEARCH (2005)
Low frequency of defective mismatch repair in a population-based series of upper urothelial carcinoma
KM Ericson et al.
BMC CANCER (2005)
PI3K/Akt signalling pathway and cancer
JAF Vara et al.
CANCER TREATMENT REVIEWS (2004)
Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2
SC Wang et al.
CANCER CELL (2004)
Hypoxia-inducible factor 1α expression correlates with angiogenesis and unfavorable prognosis in bladder cancer
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EUROPEAN UROLOGY (2004)
Multiple Roles of the PI3K/PKB (Akt) Pathway in Cell Cycle Progression
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CELL CYCLE (2003)
Src in cancer: deregulation and consequences for cell behaviour
MC Frame
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2002)
Serum levels of vascular endothelial growth factor as a prognostic factor in bladder cancer
S Bernardini et al.
JOURNAL OF UROLOGY (2001)
HIF-1: Using two hands to flip the angiogenic switch
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CANCER AND METASTASIS REVIEWS (2000)
A novel proteolytic cleavage involved in Notch signaling:: The role of the disintegrin-metalloprotease TACE
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MOLECULAR CELL (2000)