相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex
Charlotte H. Coles et al.
JOURNAL OF IMMUNOLOGY (2020)
Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells
Marc Rigau et al.
SCIENCE (2020)
Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA
Christopher J. Holland et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D
Malcolm J. W. Sim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination
Adil Doganay Duru et al.
PLOS PATHOGENS (2020)
Unleashing the immune response to NY-ESO-1 cancer testis antigen as a potential target for cancer immunotherapy
Afsheen Raza et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2020)
T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4
Charlotte H. Coles et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen
Daichao Wu et al.
NATURE COMMUNICATIONS (2020)
A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals
Louise C. Rowntree et al.
JOURNAL OF IMMUNOLOGY (2020)
Structural dissimilarity from self drives neoepitope escape from immune tolerance
Jason R. Devlin et al.
NATURE CHEMICAL BIOLOGY (2020)
Structural basis of assembly of the human T cell receptor-CD3 complex
De Dong et al.
NATURE (2019)
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1
Jerome Le Nours et al.
SCIENCE (2019)
Is TCR/pMHC Affinity a Good Estimate of the T-cell Response? An Answer Based on Predictions From 12 Phenotypic Models
Jesus Galvez et al.
FRONTIERS IN IMMUNOLOGY (2019)
Previously Hidden Dynamics at the TCR-Peptide-MHC Interface Revealed
James Fodor et al.
JOURNAL OF IMMUNOLOGY (2018)
Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide
Kok Fei Chan et al.
NATURE COMMUNICATIONS (2018)
NY-ESO-1 Based Immunotherapy of Cancer: Current Perspectives
Remy Thomas et al.
FRONTIERS IN IMMUNOLOGY (2018)
Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding
Leah V. Sibener et al.
CELL (2018)
T cell receptor cross-reactivity expanded by dramatic peptide-MHC adaptability
Timothy P. Riley et al.
NATURE CHEMICAL BIOLOGY (2018)
Flipping out the peptide
Stephanie Gras
NATURE CHEMICAL BIOLOGY (2018)
Molecular mimicry and autoimmunity
Manuel Rojas et al.
JOURNAL OF AUTOIMMUNITY (2018)
Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans
Emma J. Grant et al.
NATURE COMMUNICATIONS (2018)
Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase
David K. Cole et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene
Natalija Van Braeckel-Budimir et al.
IMMUNITY (2017)
A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβT cell receptors
Lucy C. Sullivan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Conserved Vδ1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by δ/αβ T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs
Yi Shi et al.
JOURNAL OF VIROLOGY (2017)
Quantifiable predictive features define epitope-specific T cell receptor repertoires
Pradyot Dash et al.
NATURE (2017)
Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+T cell epitope
InYoung Song et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
How an alloreactive T-cell receptor achieves peptide and MHC specificity
Yuan Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+T cell epitope
InYoung Song et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope
David K. Cole et al.
FRONTIERS IN IMMUNOLOGY (2017)
Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response
Abigail Culshaw et al.
NATURE IMMUNOLOGY (2017)
Molecular challenges imposed by MHC-I restricted long epitopes on T cell immunity
Tracy M. Josephs et al.
BIOLOGICAL CHEMISTRY (2017)
Deciphering the clinical relevance of allo-human leukocyte antigen cross-reactivity in mediating alloimmunity following transplantation
Louise C. Rowntree et al.
CURRENT OPINION IN ORGAN TRANSPLANTATION (2016)
Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response
Stephanie Gras et al.
IMMUNITY (2016)
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity
David K. Cole et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Pan-Specific Prediction of Peptide-MHC Class I Complex Stability, a Correlate of T Cell Immunogenicity
Michael Rasmussen et al.
JOURNAL OF IMMUNOLOGY (2016)
Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes
Amalie Kai Bentzen et al.
NATURE BIOTECHNOLOGY (2016)
DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity
Yang Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Molecular basis for universal HLA-A☆0201-restricted CD8+ T-cell immunity against influenza viruses
Sophie A. Valkenburg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy
Marine C. C. Raman et al.
SCIENTIFIC REPORTS (2016)
T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules
Jamie Rossjohn et al.
ANNUAL REVIEW OF IMMUNOLOGY VOL 33 (2015)
The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy
Mateusz Legut et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2015)
Human gamma delta T cells: Evolution and ligand recognition
Erin J. Adams et al.
CELLULAR IMMUNOLOGY (2015)
Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope
Xinbo Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells
Jinsung Hong et al.
JOURNAL OF IMMUNOLOGY (2015)
αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands
Richard W. Birkinshaw et al.
NATURE IMMUNOLOGY (2015)
T cell receptor dwell times control the kinase activity of Zap70
Christian Klammt et al.
NATURE IMMUNOLOGY (2015)
Accumulation of Dynamic Catch Bonds between TCR and Agonist Peptide-MHC Triggers T Cell Signaling
Baoyu Liu et al.
CELL (2014)
T cell receptor bias for MHC: co-evolution or co-receptors?
Sneha Rangarajan et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
The molecular bases of δ/αβ T cell-mediated antigen recognition
Daniel G. Pellicci et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
An Extensive Antigenic Footprint Underpins Immunodominant TCR Adaptability against a Hypervariable Viral Determinant
Usha K. Nivarthi et al.
JOURNAL OF IMMUNOLOGY (2014)
Molecular Basis of a Dominant T Cell Response to an HIV Reverse Transcriptase 8-mer Epitope Presented by the Protective Allele HLA-B*51:01
Chihiro Motozono et al.
JOURNAL OF IMMUNOLOGY (2014)
Peptide length determines the outcome of TCR/peptide-MHCI engagement
Julia Ekeruche-Makinde et al.
BLOOD (2013)
Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
Gerald P. Linette et al.
BLOOD (2013)
Crystal Structure of Vδ1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human γδ T Cells
Adrienne M. Luoma et al.
IMMUNITY (2013)
A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8+ T Cells
Kristin Ladell et al.
IMMUNITY (2013)
Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I Molecule
Yu Chih Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
CD1d-lipid antigen recognition by the γδ TCR
Adam P. Uldrich et al.
NATURE IMMUNOLOGY (2013)
The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins
Jacinto Lopez-Sagaseta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Recognition of vitamin B metabolites by mucosal-associated invariant T cells
Onisha Patel et al.
NATURE COMMUNICATIONS (2013)
Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
Akihisa Shimizu et al.
SCIENTIFIC REPORTS (2013)
Properties of MHC Class I Presented Peptides That Enhance Immunogenicity
Jorg J. A. Calis et al.
PLOS COMPUTATIONAL BIOLOGY (2013)
Six-of-the-best: unique contributions of γδ T cells to immunology
Pierre Vantourout et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Peptide-MHC class I stability is a better predictor than peptide affinity of CTL immunogenicity
Mikkel Harndahl et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
T cells and their eons-old obsession with MHC
Lei Yin et al.
IMMUNOLOGICAL REVIEWS (2012)
A Structural Basis for Varied alpha beta TCR Usage against an Immunodominant EBV Antigen Restricted to a HLA-B8 Molecule
Stephanie Gras et al.
JOURNAL OF IMMUNOLOGY (2012)
Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes
Anna M. Bulek et al.
NATURE IMMUNOLOGY (2012)
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms
Guillaume B. Stewart-Jones et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
Rachel A. Gottschalk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
TCR mechanobiology: torques and tunable structures linkec to early T cell signaling
Sun Taek Kim et al.
FRONTIERS IN IMMUNOLOGY (2012)
Why must T cells be cross-reactive?
Andrew K. Sewell
NATURE REVIEWS IMMUNOLOGY (2012)
T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex
Jarrett J. Adams et al.
IMMUNITY (2011)
A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers
Lei Yin et al.
IMMUNITY (2011)
The structural bases of direct T-cell allorecognition: implications for T-cell-mediated transplant rejection
Stephanie Gras et al.
IMMUNOLOGY AND CELL BIOLOGY (2011)
TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms
Oleg Y. Borbulevych et al.
JOURNAL OF IMMUNOLOGY (2011)
Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses
E. Bridie Day et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Dependence of T Cell Antigen Recognition on T Cell Receptor-Peptide MHC Confinement Time
Milos Aleksic et al.
IMMUNITY (2010)
Allelic polymorphism in the T cell receptor and its impact on immune responses
Stephanie Gras et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function
Daphne A. Schmid et al.
JOURNAL OF IMMUNOLOGY (2010)
The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness
Jun Huang et al.
NATURE (2010)
Fast on-rates allow short dwell time ligands to activate T cells
Christopher C. Govern et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection
John J. Miles et al.
PLOS PATHOGENS (2010)
The Shaping of T Cell Receptor Recognition by Self-Tolerance
Stephanie Gras et al.
IMMUNITY (2009)
T Cell Allorecognition via Molecular Mimicry
Whitney A. Macdonald et al.
IMMUNITY (2009)
T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity
Jennifer D. Stone et al.
IMMUNOLOGY (2009)
Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor
David K. Cole et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The αβ T Cell Receptor Is an Anisotropic Mechanosensor
Sun Taek Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition
Julia K. Archbold et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Steric Hindrance and Fast Dissociation Explain the Lack of Immunogenicity of the Minor Histocompatibility HA-1Arg Null Allele
Eric Spierings et al.
JOURNAL OF IMMUNOLOGY (2009)
Structural Bases for the Affinity-Driven Selection of a Public TCR against a Dominant Human Cytomegalovirus Epitope
Stephanie Gras et al.
JOURNAL OF IMMUNOLOGY (2009)
Complete but curtailed T-cell response to very low-affinity antigen
Dietmar Zehn et al.
NATURE (2009)
Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition
Sarah Nicholls et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Deletion of CD4 and CD8 coreceptors permits generation of αβT cells that recognize antigens independently of the MHC
Frangois Van Laethem et al.
IMMUNITY (2007)
Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'
Dan Feng et al.
NATURE IMMUNOLOGY (2007)
How a single T cell receptor recognizes both self and foreign MHC
Leremy A. Colf et al.
CELL (2007)
How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides?
Catherine Mazza et al.
EMBO JOURNAL (2007)
A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Fleur E. Tynan et al.
NATURE IMMUNOLOGY (2007)
Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines
Rachel H. McMahan et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Structural basis for a major histocompatibility complex class Ib-restricted T cell response
HL Hoare et al.
NATURE IMMUNOLOGY (2006)
T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide
FE Tynan et al.
NATURE IMMUNOLOGY (2005)
The kinetic stability of MHC class II: Peptide complexes is a key parameter that dictates immunodominance
CA Lazarski et al.
IMMUNITY (2005)
Structural and kinetic basis for heightened immunogenicity of T cell vaccines
JL Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Structure of a γδ T cell receptor in complex with the nonclassical MHC T22
EJ Adams et al.
SCIENCE (2005)
Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties
L Malherbe et al.
IMMUNITY (2004)
A correlation between TCR Vα docking on MHC and CD8 dependence:: Implications for T cell selection
J Buslepp et al.
IMMUNITY (2003)
A structural basis for immunodominant human T cell receptor recognition
GBE Stewart-Jones et al.
NATURE IMMUNOLOGY (2003)
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation
PD Holler et al.
IMMUNITY (2003)
Interplay between TCR affinity and necessity of coreceptor ligation: High-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement
SE Kerry et al.
JOURNAL OF IMMUNOLOGY (2003)
A structural basis for the selection of dominant alpha beta T cell receptors in antiviral immunity
L Kjer-Nielsen et al.
IMMUNITY (2003)
A T cell receptor CDR3 beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex
JB Reiser et al.
IMMUNITY (2002)
Most α/β T cell receptor diversity is due to terminal deoxynucleotidyl transferase
JP Cabaniols et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Crystal structure of a T cell receptor bound to an allogeneic MHC molecule
JB Reiser et al.
NATURE IMMUNOLOGY (2000)