期刊
DIABETES RESEARCH AND CLINICAL PRACTICE
卷 119, 期 -, 页码 23-31出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.diabres.2016.06.010
关键词
Diabetes; Peripheral neuropathy; Hand
资金
- University of Notre Dame Australia
Aims: Peripheral sensorimotor neuropathy is a recognised complication of diabetes mellitus however little attention has been given to its development in the hands. The aim of this study was to determine the prevalence of sensory impairment in the hands of participants with diabetes, the agreement between two measurement tools for assessing sensation and the association between hand sensibility, age, glycaemic control and end-organ damage. Methods: A total of 162 participants were recruited and divided into two cohorts based on a diagnosis of diabetes. Participants were tested for the presence of hand neuropathy using Semmes-Weinstein monofilaments and the AsTex (TM). Medical records of participants with diabetes were accessed retrospectively to determine glycaemic control and diabetes complications. Results: A highly statistically significant association was found between neuropathy and diabetes status (P < 0.001) on monofilament testing. The prevalence of neuropathy was 64% compared to similar to 10% amongst participants without diabetes. Age, male gender and diabetic retinopathy were associated with neuropathy. The AsTex (TM) identified participants with diminished protective sensation on monofilament testing. Conclusions: This study demonstrates a relationship between diabetes and upper limb neuropathy. Age, male gender and retinopathy were associated with diminished hand sensation. The AsTex (TM) may have a role as a screening tool for identifying clinically significant hand neuropathy. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
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