相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity
Shannon Lee et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
β1-Integrin binding to collagen type 1 transmits breast cancer cells into chemoresistance by activating ABC efflux transporters
Fabian Baltes et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2020)
Targeting Discoidin Domain Receptor 1 (DDR1) Signaling and Its Crosstalk with β1-Integrin Emerges as a Key Factor for Breast Cancer Chemosensitization upon Collagen Type 1 Binding
Fabian Baltes et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
A novel PI3K/mTOR dual inhibitor, CMG002, overcomes the chemoresistance in ovarian cancer
Hye Joung Choi et al.
GYNECOLOGIC ONCOLOGY (2019)
Role of the PI3K/AKT/mTOR signaling pathway in ovarian cancer: Biological and therapeutic significance
Meran Keshawa Ediriweera et al.
SEMINARS IN CANCER BIOLOGY (2019)
Delineation of crosstalk between HSP27 and MMP-2/MMP-9: A synergistic therapeutic avenue for glioblastoma management
Y. Rajesh et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2019)
Inhibition of PI3K/Akt/mTOR signaling pathway alleviates ovarian cancer chemoresistance through reversing epithelial-mesenchymal transition and decreasing cancer stem cell marker expression
Junli Deng et al.
BMC CANCER (2019)
A Comprehensive Review on MAPK: A Promising Therapeutic Target in Cancer
Cornelia Braicu et al.
CANCERS (2019)
The Impact of Integrin-Mediated Matrix Adhesion on Cisplatin Resistance of W1 Ovarian Cancer Cells
Kathleen Wantoch von Rekowski et al.
BIOMOLECULES (2019)
Epidemiology of ovarian cancer in Germany
Nina Buttmann-Schweiger et al.
ONKOLOGE (2019)
Targeting the PI3K pathway in cancer: are we making headway?
Filip Janku et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation
Angela Russo et al.
ONCOGENE (2018)
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
Signaling by discoidin domain receptor 1 in cancer metastasis
Mayur Gadiya et al.
CELL ADHESION & MIGRATION (2018)
A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers
Tonci Sustic et al.
GENOME MEDICINE (2018)
Inhibition of MMP-2 Expression Enhances the Antitumor Effect of Sorafenib in Hepatocellular Carcinoma by Suppressing the PI3K/AKT/mTOR Pathway
Wenliang Tan et al.
ONCOLOGY RESEARCH (2017)
Targeting the unfolded protein response in cancer
Rani Ojha et al.
PHARMACOLOGICAL RESEARCH (2017)
Suppressing miR-199a-3p by promoter methylation contributes to tumor aggressiveness and cisplatin resistance of ovarian cancer through promoting DDR1 expression
Yuao Deng et al.
JOURNAL OF OVARIAN RESEARCH (2017)
Evaluation of the combination of the dual m-TORC1/2 inhibitor vistusertib (AZD2014) and paclitaxel in ovarian cancer models
Anne-Christine Wong Te Fong et al.
ONCOTARGET (2017)
Integrin Activation Contributes to Lower Cisplatin Sensitivity in MV3 Melanoma Cells by Inducing the Wnt Signalling Pathway
Maria B. R. Piva et al.
CANCERS (2017)
Epidemiology of ovarian cancer: a review
Brett M. Reid et al.
CANCER BIOLOGY & MEDICINE (2017)
Role of the unfolded protein response in tumor cell characteristics and cancer outcome
Antoine Galmiche et al.
CURRENT OPINION IN ONCOLOGY (2017)
Time-staggered inhibition of JNK effectively sensitizes chemoresistant ovarian cancer cells to cisplatin and paclitaxel
Manabu Seino et al.
ONCOLOGY REPORTS (2016)
Survivin is a guardian of the intestinal stem cell niche and its expression is regulated by TGF-
Eva Martini et al.
CELL CYCLE (2016)
New HSP27 inhibitors efficiently suppress drug resistance development in cancer cells
Joerg C. Heinrich et al.
ONCOTARGET (2016)
Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases
Eleonore Beurel et al.
PHARMACOLOGY & THERAPEUTICS (2015)
The Regulation of Matrix Metalloproteinase Expression and the Role of Discoidin Domain Receptor 1/2 Signalling in Zoledronate-treated PC3 Cells
Buket Reel et al.
JOURNAL OF CANCER (2015)
PTEN: multiple functions in human malignant tumors
Michele Milella et al.
FRONTIERS IN ONCOLOGY (2015)
Sorafenib resistance and JNK signaling in carcinoma during extracellular matrix stiffening
Thuy V. Nguyen et al.
BIOMATERIALS (2014)
HSP27 phosphorylation modulates TRAIL-induced activation of Src-Akt/ERK signaling through interaction with β-arrestin2
Shimei Qi et al.
CELLULAR SIGNALLING (2014)
Automated quantitative multiplex immunofluorescence in situ imaging identifies phospho-S6 and phospho-PRAS40 as predictive protein biomarkers for prostate cancer lethality
Michail Shipitsin et al.
PROTEOME SCIENCE (2014)
Overcoming chemotherapy resistance of ovarian cancer cells by liposomal cisplatin: Molecular mechanisms unveiled by gene expression profiling
Martin Koch et al.
BIOCHEMICAL PHARMACOLOGY (2013)
Hsp27 Regulates Epithelial Mesenchymal Transition, Metastasis, and Circulating Tumor Cells in Prostate Cancer
Masaki Shiota et al.
CANCER RESEARCH (2013)
TRAIL/MEKK4/p38/HSP27/Akt survival network is biphasically modulated by the Src/CIN85/c-Cbl complex
Jina Kim et al.
CELLULAR SIGNALLING (2013)
MDR Gene Expression Analysis of Six Drug-Resistant Ovarian Cancer Cell Lines
Radoslaw Januchowski et al.
BIOMED RESEARCH INTERNATIONAL (2013)
Inside-out, outside-in, and inside-outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction
Bo Shen et al.
CURRENT OPINION IN CELL BIOLOGY (2012)
Targeting the MAPK-RAS-RAF signaling pathway in cancer therapy
Libero Santarpia et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2012)
MAMMALIAN MAPK SIGNAL TRANSDUCTION PATHWAYS ACTIVATED BY STRESS AND INFLAMMATION: A 10-YEAR UPDATE
John M. Kyriakis et al.
PHYSIOLOGICAL REVIEWS (2012)
Heat shock protein 27 (HSP27): biomarker of disease and therapeutic target
Aparna Vidyasagar et al.
FIBROGENESIS & TISSUE REPAIR (2012)
Global Cancer Statistics
Ahmedin Jemal et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2011)
Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production
M. E. Roberts et al.
EUROPEAN RESPIRATORY JOURNAL (2011)
Identification of Receptor Tyrosine Kinase, Discoidin Domain Receptor 1 (DDR1), as a Potential Biomarker for Serous Ovarian Cancer
Jinhua Quan et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2011)
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
Marie Cargnello et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2011)
Pathological roles of MAPK signaling pathways in human diseases
Eun Kyung Kim et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Integrins in cancer: biological implications and therapeutic opportunities
Jay S. Desgrosellier et al.
NATURE REVIEWS CANCER (2010)
Small Interfering RNA-mediated Silencing of Heat Shock Protein 27 (HSP27) Increases Chemosensitivity to Paclitaxel by Increasing Production of Reactive Oxygen Species in Human Ovarian Cancer Cells (HO8910)
T. F. Song et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2009)
Effects of collagen IV on cisplatin-induced apoptosis of non-small cell lung cancer cells
Chunxia Su et al.
CANCER INVESTIGATION (2007)
PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding
Lifu Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
PRAS40 deregulates apoptosis in malignant melanoma
SubbaRao V. Madhunapantula et al.
CANCER RESEARCH (2007)
Activation of p70S6K induces expression of matrix metalloproteinase 9 associated with hepatocyte growth factor-mediated invasion in human ovarian cancer cells
HY Zhou et al.
ENDOCRINOLOGY (2006)
Therapeutic targets - MTOR and related pathways
Janet E. Dancey
CANCER BIOLOGY & THERAPY (2006)
Heat shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer
P Rocchi et al.
CANCER RESEARCH (2004)
Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells
CA Sherman-Baust et al.
CANCER CELL (2003)
Antiapoptotic action of focal adhesion kinase (FAK) against ionizing radiation
T Kasahara et al.
ANTIOXIDANTS & REDOX SIGNALING (2002)
Discoidin domain receptor 1 is activated independently of β1 integrin
W Vogel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)