期刊
INTERNATIONAL JOURNAL OF HEMATOLOGY
卷 113, 期 3, 页码 330-336出版社
SPRINGER JAPAN KK
DOI: 10.1007/s12185-021-03078-x
关键词
COVID-19; Thromboembolism; Deep vein thrombus; Thromboprophylaxis; Ethnic difference
类别
资金
- Promotion and Mutual Aid Corporation for Private Schools of Japan
There may be differences in thrombosis and bleeding among different ethnicities in COVID-19 patients, with a lower incidence of thromboembolic events in the Asian population. Despite bleeding being a side effect, current evidence supports routine anticoagulant use and thromboprophylaxis using a standard dose of LMWH for admitted patients.
Thromboembolic events contribute to morbidity and mortality in coronavirus disease 2019 (COVID-19). As a result, thromboprophylaxis using low-molecular-weight heparin (LMWH) is universally recommended for hospitalized patients based on multiple guidelines. However, ethnic differences with respect to thrombogenicity have been reported and the incidence of thromboembolic events is considered to be lower in the Asian population. Despite the importance of thromboprophylaxis, bleeding is also a side effect that should be considered. We examine the data relating to potential ethnic differences in thrombosis and bleeding in COVID-19. Although sufficient data is not yet available, current evidence does not oppose routine anticoagulant use and thromboprophylaxis using a standard dose of LMWH for admitted patients regardless of ethnicity based on our review.
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