期刊
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
卷 155, 期 1, 页码 125-131出版社
WILEY
DOI: 10.1002/ijgo.13602
关键词
depression; longitudinal studies; postpartum period; pregnancy; sleep
资金
- Research of Korea Centers for Disease and Prevention [2013-E63009-00, 2013-E63009-01, 2015-ER6302-00, 2016-ER6306-00, 2016-ER6306-01]
- Korea Health Promotion Institute [2015-ER6302-00, 2013-E63009-01, 2013-E63009-00, 2016-ER6306-01, 2016-ER6306-00] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Insufficient sleep, especially at 36 weeks of pregnancy, is associated with an increased risk of developing postpartum depression (PPD). Regardless of previous sleep patterns, a worsening of sleep at 36 weeks gestation is highly correlated with PPD.
Objective To determine the association between insufficient sleep in the prenatal period and postpartum depression (PPD), and whether changes in sleep patterns during pregnancy increase the risk of PPD. Methods A prospective cohort study was conducted between March 2013 and November 2017. Participants completed a sleep questionnaire pre-pregnancy and at 12, 24 and 36 gestational weeks (GW). Depressive symptoms were assessed by the Edinburgh Postnatal Depression Scale (EPDS) at 4 weeks postpartum, and the cut-off score for PPD was 10 or more. Results Of 2512 participants, 410 (16.3%) were identified as having PPD. Only insufficient sleep at 36 GW was significantly associated with PPD after adjusting for confounding factors (odds ratio 1.79, 95% confidence interval 1.40-2.27, P < 0.001). Both Group 1 (change from sufficient to insufficient) and Group 3 (sustained insufficient) demonstrated a significant risk of PPD at all starting time-points in the multivariate analysis, but no significant association was evident between Group 2 (change from insufficient to sufficient) and PPD. Conclusion Insufficient sleep at 36 GW was associated with a significant risk of developing PPD. Additionally, regardless of whether women had sufficient sleep, a shift towards worsening sleep at 36 GW was highly associated with PPD.
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