期刊
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
卷 32, 期 6, 页码 1192-1203出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09603123.2020.1860200
关键词
Aflatoxin M1; ochratoxin A; human breast milk; season; lactational stage
The study found that different seasons and lactation stages can affect the levels of aflatoxin M1 and ochratoxin A in human breast milk, while factors such as maternal smoking habits, body mass index, history of moldy food exposure, birth order, and breastfeeding type did not influence the results.
The aim was to evaluate the changes in aflatoxin M1 (AFM1) and ochratoxin A (OTA) levels in human breast milk (HBM) during the first five postpartum months according to the sampling season in a cohort study from Sanliurfa. From 78 healthy lactating mothers, HBM was taken at the 5-14 days postpartum (D5-14) and the 6(th) and 18(th) weeks postpartum (W6 and W18). Mycotoxin levels were analyzed with competitive ELISA. Generalized Estimating Equations with repeated measures (three-correlation matrix dimension) revealed a significantly higher mean AFM1 level at W6 than that on D5-14. AFM1 and OTA levels in winter and spring were considerably higher than that in summer and autumn. Maternal smoke exposure, body mass index, history of moldy food exposure, birth order, and breastfeeding type did not influence the results. Whilst season had a marked effect on the milk levels of both analytes, lactation stage affected AFM1 more notable than OTA.
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