Inflammation as a determinant of healing response after coronary stent implantation

Cardiovascular disease remains the leading cause of death and morbidity worldwide. Inflammation plays an important role in the development of atherosclerosis and is associated with adverse clinical outcomes in patients after percutaneous coronary interventions. Data on stent elements that lead to excessive inflammatory response, proper identification of high-risk patients, prevention and treatment targeting residual inflammatory risk are limited. This review aims to present the role of inflammation in the context of evolving stent technologies and appraise the potential imaging modalities in detection of inflammatory response and anti-inflammatory therapies.

Automated summary

This review highlights the important role of inflammation in atherosclerosis development and adverse clinical outcomes in patients post percutaneous coronary interventions. Limited data on stent elements causing excessive inflammatory response and strategies for high-risk patient identification, prevention, and treatment were discussed. The review also evaluates the potential imaging modalities for detecting inflammatory response and anti-inflammatory therapies in the context of evolving stent technologies.