相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in patients with newly diagnosed malignant glioma
Antje Wick et al.
INVESTIGATIONAL NEW DRUGS (2020)
The Role of Periarticular Soft Tissues in Persistent Motion Loss in a Rat Model of Posttraumatic Elbow Contracture
Chelsey L. Dunham et al.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2019)
Spontaneous differentiation of periodontal ligament stem cells into myofibroblast during ex vivo expansion
Kengo Iwasaki et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Novel transforming growth factor beta receptor I kinase inhibitor galunisertib (LY2157299) in advanced hepatocellular carcinoma
Sandrine Faivre et al.
LIVER INTERNATIONAL (2019)
A Phase 2 Study of Galunisertib (TGF-β1 Receptor Type I Inhibitor) and Sorafenib in Patients With Advanced Hepatocellular Carcinoma
R. K. Kelley et al.
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2019)
Phase II Study of the ALK5 Inhibitor Galunisertib in Very Low-, Low-, and Intermediate-Risk Myelodysplastic Syndromes
Valeria Santini et al.
CLINICAL CANCER RESEARCH (2019)
TGF-β in fibrosis by acting as a conductor for contractile properties of myofibroblasts
Alexandre Vallee et al.
CELL AND BIOSCIENCE (2019)
Pathological mechanisms and therapeutic outlooks for arthrofibrosis
Kayley M. Usher et al.
BONE RESEARCH (2019)
Intra-articular injection of a substance P inhibitor affects gene expression in a joint contracture model
Mark E. Morrey et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2018)
Accumulation of advanced-glycation end products (AGEs) accelerates arthrogenic joint contracture in immobilized rat knee
Junya Ozawa et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2018)
Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-β receptor type I inhibitor
Jonathan M. Yingling et al.
Oncotarget (2018)
Active exercise on immobilization-induced contractured rat knees develops arthrogenic joint contracture with pathological changes
Akinori Kaneguchi et al.
JOURNAL OF APPLIED PHYSIOLOGY (2018)
Joint contracture is reduced by intra-articular implantation of rosiglitazone-loaded hydrogels in a rabbit model of arthrofibrosis
Diren Arsoy et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2018)
Development of arthrogenic joint contracture as a result of pathological changes in remobilized rat knees
Akinori Kaneguchi et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2017)
Cyclooxygenase-2 inhibitor celecoxib attenuates joint contracture following immobilization in rat knees
Junya Ozawa et al.
BMC MUSCULOSKELETAL DISORDERS (2016)
First-in-Human Dose Study of the Novel Transforming Growth Factor-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Patients with Advanced Cancer and Glioma
Jordi Rodon et al.
CLINICAL CANCER RESEARCH (2015)
Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer
Jordi Rodon et al.
INVESTIGATIONAL NEW DRUGS (2015)
Quantitative analysis of the reversibility of knee flexion contractures with time: an experimental study using the rat model
Guy Trudel et al.
BMC MUSCULOSKELETAL DISORDERS (2014)
Contributions of biarticular myogenic components to the limitation of the range of motion after immobilization of rat knee joint
Momoko Nagai et al.
BMC MUSCULOSKELETAL DISORDERS (2014)
Transforming Growth Factor-β as a Therapeutic Target in Hepatocellular Carcinoma
Gianluigi Giannelli et al.
CANCER RESEARCH (2014)
High-Dosage Tamoxifen as Neoadjuvant Treatment in Minimally Invasive Surgery for Dupuytren Disease in Patients with a Strong Predisposition Toward Fibrosis
Ilse Degreef et al.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2014)
Lentivirus-Mediated ERK2 siRNA Reduces Joint Capsule Fibrosis in a Rat Model of Post-Traumatic Joint Contracture
Fengfeng Li et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
Gehua Zhen et al.
NATURE MEDICINE (2013)
Treadmill running and static stretching improve long-lasting hyperalgesia, joint limitation, and muscle atrophy induced by cast immobilization in rats
Atsuko Morimoto et al.
NEUROSCIENCE LETTERS (2013)
Myofibroblast cells are preferentially expressed early in a rabbit model of joint contracture
Matthew P. Abdel et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2012)
Effects of Prolonged Stretching and Thermotherapy on Muscle Contracture of Immobilized Rat Soleus Muscle
Yasutaka Kondo et al.
JOURNAL OF PHYSICAL THERAPY SCIENCE (2012)
Targeting the TGFβ signalling pathway in disease
Rosemary J. Akhurst et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
TGFβ signalling in context
Joan Massague
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Elbow joint contracture after traumatic injury
Curtis Myden et al.
JOURNAL OF SHOULDER AND ELBOW SURGERY (2011)
New Rabbit Knee Model of Posttraumatic Joint Contracture: Indirect Capsular Damage Induces a Severe Contracture
Sergiy Nesterenko et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2009)
TGF-β1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
Yi Tang et al.
NATURE MEDICINE (2009)
Cellular, matrix, and growth factor components of the joint capsule are modified early in the process of posttraumatic contracture formation in a rabbit model
Kevin A. Hildebrand et al.
ACTA ORTHOPAEDICA (2008)
Experimental joint contracture correction with low torque - Long duration repeated stretching
M. Usuba et al.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2007)
Myofibroblast upregulators are elevated in joint capsules in posttraumatic contractures
Kevin A. Hildebrand et al.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2007)
High rate of joint capsule matrix turnover in chronic human elbow contractures
KA Hildebrand et al.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2005)
Rabbit knee model of post-traumatic joint contractures: the long-term natural history of motion loss and myofibroblasts
KA Hildebrand et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2004)
Different frequency treadmill running in immobilization-induced muscle atrophy and ankle joint contracture of rats
H Sakakima et al.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS (2004)
The immunosuppressant rapamycin, alone or with transforming growth factor-β, enhances osteoclast differentiation of RAW264.7 monocyte-macrophage cells in the presence of RANK-ligand
C Shui et al.
CALCIFIED TISSUE INTERNATIONAL (2002)
分享论文
