4.4 Article

APR-246 induces early cell death by ferroptosis in acute myeloid leukemia

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation

Michael M. Gaschler et al.

NATURE CHEMICAL BIOLOGY (2018)

Article Medicine, General & Internal

Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML

C. D. DiNardo et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Cell Biology

APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

Qiang Zhang et al.

CELL DEATH & DISEASE (2018)

Article Biochemistry & Molecular Biology

Unsolved mysteries: How does lipid peroxidation cause ferroptosis?

Huizhong Feng et al.

PLOS BIOLOGY (2018)

Review Biochemistry & Molecular Biology

Ferroptosis, a Recent Defined Form of Critical Cell Death in Neurological Disorders

Jia-rui Wu et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2018)

Article Biochemistry & Molecular Biology

Glutathione peroxidase 4: a new player in neurodegeneration?

B. R. Cardoso et al.

MOLECULAR PSYCHIATRY (2017)

Article Medicine, General & Internal

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

R. M. Stone et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Biochemistry & Molecular Biology

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Brent R. Stockwell et al.

Article Biochemical Research Methods

SynergyFinder: a web application for analyzing drug combination dose-response matrix data

Aleksandr Ianevski et al.

BIOINFORMATICS (2017)

Article Biochemistry & Molecular Biology

Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang et al.

Article Cell Biology

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Jose Pedro Friedmann Angeli et al.

NATURE CELL BIOLOGY (2014)

Article Oncology

PRIMA-1Met/APR-246 Displays High Antitumor Activity in Multiple Myeloma By Induction of p73 and Noxa

Manujendra N. Saha et al.

MOLECULAR CANCER THERAPEUTICS (2013)

Article Biochemistry & Molecular Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon et al.

Article Biochemistry & Molecular Biology

Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis

J. M. R. Lambert et al.

ONCOGENE (2010)

Article Oncology

PRIMA-1 Reactivates Mutant p53 by Covalent Binding to the Core Domain

Jeremy M. R. Lambert et al.

CANCER CELL (2009)

Article Hematology

PRIMA-1 induces apoptosis in acute myeloid leukaemia cells with p53 gene deletion

H Nahi et al.

BRITISH JOURNAL OF HAEMATOLOGY (2006)

Article Biochemistry & Molecular Biology

PRIMA-1MET synergizes with cisplatin to induce tumor cell apoptosis

VJN Bykov et al.

ONCOGENE (2005)

Article Biochemistry & Molecular Biology

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound

VJN Bykov et al.

NATURE MEDICINE (2002)