期刊
EUROPEAN JOURNAL OF PEDIATRICS
卷 180, 期 6, 页码 1739-1745出版社
SPRINGER
DOI: 10.1007/s00431-020-03924-w
关键词
Pediatric psoriasis; Childhood psoriasis; Metabolic syndrome; Insulin resistance; HOMA-IR; Psoriasis
类别
资金
- Universita degli Studi di Padova
This study investigated the prevalence of metabolic syndrome and insulin resistance in 60 pre-pubertal children with psoriasis, finding that 30% had metabolic syndrome and 27% had insulin resistance. The data highlight the importance of assessing metabolic syndrome in young children with psoriasis besides adults and adolescents.
Psoriasis in adults is associated with an increased risk of metabolic disease. Various cardiometabolic comorbidities have been reported in childhood psoriasis, but only a few studies have analyzed the prevalence of metabolic syndrome. We performed a single-center prospective study investigating the prevalence of metabolic syndrome and insulin resistance in children with psoriasis. The prevalence of metabolic syndrome was evaluated in 60 pre-pubertal children with psoriasis (age: 3-10 years), accordingly to recently established criteria for the diagnosis of metabolic syndrome in children. Insulin resistance was considered altered when the homeostatic model assessment (HOMA-IR) for insulin resistance was >= 90th sex- and age-specific percentile and HOMA 2-IR was > 1.8. Eighteen (30%) children with psoriasis were found to have metabolic syndrome. Sixteen (27%) children were found to have insulin resistance. Conclusion: Our data underline the importance of assessing metabolic syndrome not only in adults and adolescents but also in young children with psoriasis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据